HsaEX0069757 @ hg38
Exon Skipping
Gene
ENSG00000077254 | USP33
Description
ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:HGNC:20059]
Coordinates
chr1:77725622-77726979:-
Coord C1 exon
chr1:77726879-77726979
Coord A exon
chr1:77726521-77726638
Coord C2 exon
chr1:77725622-77725762
Length
118 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTCCTGAAACAGGGT
3' ss Score
9.03
5' ss Seq
CAGGTGTAC
5' ss Score
2.59
Exon sequences
Seq C1 exon
CTCTTACGAACAATTCTCTTTTCTTCACTCAAATAGTTACTGAGCACATTCCCTTGCCCTGGAATATGTTAGGCACTAGGAATCCAAAGCAAACAATCAAG
Seq A exon
GGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCACATCTCACCACAGCCTCAACCTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCTCTTGAGTAGCCAGCACTACAG
Seq C2 exon
AATATATCACTGATGTCCATTCGAATGACCTGTCTACACCACAGATCCTTCCATCAAATGAAGGTGTTAATCCACGTTTATCGGCAAGCCCTCCTAAATCAGGCAATTTGTGGCCAGGATTGGCACCACCACACAAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000077254-'31-30,'31-29,32-30
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.318 A=1.000 C2=0.830
Domain overlap (PFAM):
C1:
PF0044324=UCH=FE(6.9=100)
A:
PF139001=GVQW=WD(100=81.5)
C2:
PF0044324=UCH=FE(13.6=100)
Main Inclusion Isoform:
ENST00000370793fB7608
Main Skipping Isoform:
ENST00000370793fB7607
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAACAATTCTCTTTTCTTCACTCA
R:
TTTTTGTGTGGTGGTGCCA
Band lengths:
235-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development