HsaEX0070256 @ hg38
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133785776-133788486:-
Coord C1 exon
chr9:133788354-133788486
Coord A exon
chr9:133787920-133787973
Coord C2 exon
chr9:133785776-133785885
Length
54 bp
Sequences
Splice sites
3' ss Seq
GCCCATGTTGTCCCTTGTAGCAA
3' ss Score
8.53
5' ss Seq
TGGGTAGGT
5' ss Score
6.86
Exon sequences
Seq C1 exon
GTACTTGTTCCTGTTTGACAAGGTGGTCATCGTCTGCAAGCGGAAGGGCTACAGCTACGAGCTCAAGGAGATCATCGAGCTGCTGTTCCACAAGATGACCGACGACCCCATGAACAACAAGGACGTCAAGAAG
Seq A exon
CAAGCAGGCTTTCCTCTCCCGTCCCACCCTGCGGTGCTTGGAGGAGGGCTGTGG
Seq C2 exon
TGGTCCTACGGCTTCTACCTAATTCACCTTCAAGGAAAGCAGGGCTTCCAGTTTTTCTGCAAAACAGAAGATATGAAGAGGAAGTGGATGGAGCAGTTTGAGATGGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293_MULTIEX2-2/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.041 A=0.056 C2=0.036
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(41.1=100)
A:
PF0016924=PH=FE(13.6=100)
C2:
PF0016924=PH=FE(33.6=100)
Main Inclusion Isoform:
ENST00000371850fB7688
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACGACCCCATGAACAACAA
R:
GGCCATCTCAAACTGCTCCAT
Band lengths:
142-196
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development