HsaEX0070258 @ hg38
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133785776-133788486:-
Coord C1 exon
chr9:133788354-133788486
Coord A exon
chr9:133787246-133787260
Coord C2 exon
chr9:133785776-133785885
Length
15 bp
Sequences
Splice sites
3' ss Seq
CTCCTCTCCATGCTTCCTAGTCT
3' ss Score
6.12
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
Exon sequences
Seq C1 exon
GTACTTGTTCCTGTTTGACAAGGTGGTCATCGTCTGCAAGCGGAAGGGCTACAGCTACGAGCTCAAGGAGATCATCGAGCTGCTGTTCCACAAGATGACCGACGACCCCATGAACAACAAGGACGTCAAGAAG
Seq A exon
TCTCACGGGAAAATG
Seq C2 exon
TGGTCCTACGGCTTCTACCTAATTCACCTTCAAGGAAAGCAGGGCTTCCAGTTTTTCTGCAAAACAGAAGATATGAAGAGGAAGTGGATGGAGCAGTTTGAGATGGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293-'57-40,'57-39,60-40
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.041 A=0.000 C2=0.036
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(41.1=100)
A:
PF0016924=PH=FE(3.7=100)
C2:
PF0016924=PH=FE(33.6=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTGTTCCACAAGATGACCG
R:
TGCAGAAAAACTGGAAGCCCT
Band lengths:
114-129
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development