HsaEX0070262 @ hg19
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav 2 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12658]
Coordinates
chr9:136726496-136804341:-
Coord C1 exon
chr9:136804225-136804341
Coord A exon
chr9:136792918-136793014
Coord C2 exon
chr9:136726496-136726554
Length
97 bp
Sequences
Splice sites
3' ss Seq
TGCCTCAACCCTGCTCACAGGAT
3' ss Score
6.91
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
Exon sequences
Seq C1 exon
TTTCTGTGTTTGAAGAACATACGCACCTTCCTGAAAGTCTGCCACGATAAATTTGGATTAAGGAACAGCGAGCTGTTTGACCCCTTTGACCTCTTCGATGTGCGAGACTTTGGAAAG
Seq A exon
GATCCTAGGAGGCTGTGATTTCAAGACCTGAGTTCAAGCTCTGGGAGCGGCCTTGGCCCATGAGTGGATCCCTTGATCTCCATGCCAGTGGTGTGAG
Seq C2 exon
GTCATCTCCGCGGTGTCGAGGCTCTCCCTGCACAGCATCGCGCAGAACAAAGGGATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.022
Domain overlap (PFAM):
C1:
PF119713=CAMSAP_CH=PD(39.5=87.2)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTGAAGAACATACGCACCTTCC
R:
GATCCCTTTGTTCTGCGCGAT
Band lengths:
167-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)