HsaEX0070262 @ hg38
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133861374-133939219:-
Coord C1 exon
chr9:133939103-133939219
Coord A exon
chr9:133927796-133927892
Coord C2 exon
chr9:133861374-133861432
Length
97 bp
Sequences
Splice sites
3' ss Seq
TGCCTCAACCCTGCTCACAGGAT
3' ss Score
6.91
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
Exon sequences
Seq C1 exon
TTTCTGTGTTTGAAGAACATACGCACCTTCCTGAAAGTCTGCCACGATAAATTTGGATTAAGGAACAGCGAGCTGTTTGACCCCTTTGACCTCTTCGATGTGCGAGACTTTGGAAAG
Seq A exon
GATCCTAGGAGGCTGTGATTTCAAGACCTGAGTTCAAGCTCTGGGAGCGGCCTTGGCCCATGAGTGGATCCCTTGATCTCCATGCCAGTGGTGTGAG
Seq C2 exon
GTCATCTCCGCGGTGTCGAGGCTCTCCCTGCACAGCATCGCGCAGAACAAAGGGATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293_MULTIEX4-2/5=1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF119713=CAMSAP_CH=PD(39.5=87.2)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTGAAGAACATACGCACCTTCC
R:
GATCCCTTTGTTCTGCGCGAT
Band lengths:
167-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development