HsaEX0070270 @ hg19
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav 3 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12659]
Coordinates
chr1:108319853-108322114:-
Coord C1 exon
chr1:108322056-108322114
Coord A exon
chr1:108320292-108320392
Coord C2 exon
chr1:108319853-108319918
Length
101 bp
Sequences
Splice sites
3' ss Seq
ATGTTTTTGTCTTCTACTAGTTT
3' ss Score
8.08
5' ss Seq
AGGGTACAT
5' ss Score
3.77
Exon sequences
Seq C1 exon
GTTATAGAAACATTATCACGACTTTCTCGAACACCTATAGCATTGGCCACAGGAATCAG
Seq A exon
TTTTCATCTACACTAGTGAACGGAGCCATGGAAGGATGATTGCTACCAAATTATTTGTTATCAGATCCCACAGCTGAAAAGAGAGGGTGCTGAAGGCAAGG
Seq C2 exon
GCCCTTCCCAACAGAAGAAAGCATTAATGATGAAGACATCTACAAAGGCCTTCCTGATTTAATAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.029
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAACATTATCACGACTTTCTCGA
R:
AAATCAGGAAGGCCTTTGTAGATGT
Band lengths:
114-215
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)