HsaEX0070588 @ hg19
Exon Skipping
Gene
ENSG00000139722 | VPS37B
Description
vacuolar protein sorting 37 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25754]
Coordinates
chr12:123355437-123380991:-
Coord C1 exon
chr12:123380499-123380991
Coord A exon
chr12:123363876-123364052
Coord C2 exon
chr12:123355437-123355608
Length
177 bp
Sequences
Splice sites
3' ss Seq
CATGCACTTCTCACTTCCAGGCC
3' ss Score
10.03
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
Exon sequences
Seq C1 exon
GGGCTCACAGGCTGCGGGAACTTCCTTCCCACTGCCTGTTTTCCTTGGATCGCGGTATCTCTCTTCCTGGAGGAAAAAGGCTCTTATGACCTCATGGCGCGCTCTCCCGAGCCGCAGTGACGTCATTAATGCGCTCACGCGTCACAGCCCAATCATAGGGCCCTTCCCCTCCCTTTAGAAGTCCCGACTGTCCCTGACACATTCCACTCCAAGCGAGCCGCGACACTTACGTCACGTCCGCCCGCCCGCGCGGTGATGACGTCACGACCCAGGGCTGGCGTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGGCGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAG
Seq A exon
GCCTGCGGGAGGGGCAGAGGAGAGGGCTGCCTTGGAGGAAGGGAGGGTTGGAGGACCTGGCCCAGCTGCAGCCGCACCTCAGCGAGGCAACCCGGGGAACACTCCCCATCTCCGCTGTCCCTTTTCATCTTCCTCCTACTGTTGATCCTCATTGCTGAATCCAACCAGAACCTGAGG
Seq C2 exon
ACACAGAATGTTCAGCTTAACAAAGAAATGACACTTGCCAGCAACCGGAGCCTGGCAGAAGGAAACCTTTTGTACCAGCCCCAGCTGGACACGTTGAAAGCACGCTTGACCCAGAAATACCAGGAACTCCAGGTTCTCTTTGAAGCCTATCAGATAAAGAAGACCAAATTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139722-'0-2,'0-0,1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.171 A=0.203 C2=0.095
Domain overlap (PFAM):
C1:
PF072008=Mod_r=PU(54.0=73.0),PF0127615=OKR_DC_1=PU(36.0=73.0)
A:
PF072008=Mod_r=PU(8.9=20.3)
C2:
PF072008=Mod_r=FE(37.2=100),PF142471=DUF4344=FE(55.6=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCGAGACGTGGGGATGG
R:
TTTCTGGGTCAAGCGTGCTTT
Band lengths:
242-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)