HsaEX0073057 @ hg19
Exon Skipping
Gene
ENSG00000196387 | ZNF140
Description
zinc finger protein 140 [Source:HGNC Symbol;Acc:12925]
Coordinates
chr12:133660052-133684260:+
Coord C1 exon
chr12:133660052-133660147
Coord A exon
chr12:133677573-133677639
Coord C2 exon
chr12:133682096-133684260
Length
67 bp
Sequences
Splice sites
3' ss Seq
CTTTTAAATATTGAACAAAGGTA
3' ss Score
1.63
5' ss Seq
TAGGTAAGG
5' ss Score
9.31
Exon sequences
Seq C1 exon
GTCTTTCCATTTCTAAGCCAGATGTGGTTTCCTTATTGGAGCAAGGGAAAGAACCCTGGCTGGGGAAAAGGGAAGTGAAAAGAGATCTGTTTTCAG
Seq A exon
GTAACTGAAGTGGTGAAAAACTACAGAGGAGAGGACTACTGTAATTCCCAGCCTTGTTCCTTTATAG
Seq C2 exon
TTTCAGAGTCAAGTGGTGAGATCAAAGACTTTTCACCAAAAAATGTCATTTATGATGACTCATCCCAGTATTTGATCATGGAAAGAATTCTAAGTCAAGGCCCTGTGTATTCCAGTTTTAAAGGAGGCTGGAAATGCAAGGATCATACTGAGATGCTGCAAGAAAATCAGGGATGTATTAGGAAAGTAACAGTCTCTCATCAAGAAGCCCTGGCTCAACATATGAATATCAGTACTGTGGAGAGGCCCTATGGATGCCATGAATGTGGAAAAACTTTTGGTCGACGCTTTTCCCTGGTGTTACACCAGAGGACTCATACTGGAGAGAAACCATATGCATGTAAGGAATGTGGCAAAACCTTTAGCCAGATTTCAAACCTTGTGAAACACCAAATGATACATACTGGAAAGAAACCCCATGAGTGTAAGGACTGTAATAAAACATTCAGTTACCTTTCATTTCTTATTGAACACCAGAGAACGCACACTGGGGAGAAACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196387_MULTIEX1-7/7=5-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NO
C2:
PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.3),PF097235=Zn-ribbon_8=WD(100=11.8),PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.0),PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=6.8),PF134651=zf-H2C2_2=WD(100=7.3),PF134651=zf-H2C2_2=WD(100=7.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGGGAAAAGGGAAGTGAA
R:
CCTTGCATTTCCAGCCTCCTT
Band lengths:
179-246
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)