HsaEX0073462 @ hg19
Exon Skipping
Gene
ENSG00000189180 | ZNF33A
Description
zinc finger protein 33A [Source:HGNC Symbol;Acc:13096]
Coordinates
chr10:38306219-38348991:+
Coord C1 exon
chr10:38306219-38306314
Coord A exon
chr10:38323206-38323328
Coord C2 exon
chr10:38343303-38348991
Length
123 bp
Sequences
Splice sites
3' ss Seq
AATGTCCTTCTTTGTTCCAGGAT
3' ss Score
10.63
5' ss Seq
GAGGTATAT
5' ss Score
7.3
Exon sequences
Seq C1 exon
GGTATTGTGTTCACAAACCAGAGGTGATCTTCAGGCTGCAACAAGGAGAAGAGCCATGGAAACAGGAGGAAGAATTCCCAAGCCAAAGCTTTCCAG
Seq A exon
GATCCCTTCCAGGGCACCATATTACATTTAGTTGTCATGTCTCTTTAGGCTCCTCTTGGCTATGGTGGTTTCCCAGACTTTCCTTGTTTTGGATGACCTTGACAGTTGAGGAGTCCTGGTGAG
Seq C2 exon
AAGTCTGGACAGCTGATCACCTGAAAGAGAGGAGCCAAGAAAACCAATCTAAACATTTGTGGGAAGTTGTATTCATCAATAATGAAATGCTGACTAAGGAACAAGGTGATGTAATAGGAATACCATTTAATGTGGATGTAAGTTCTTTTCCTTCCAGAAAAATGTTCTGTCAGTGTGATTCATGTGGAATGAGTTTCAACACTGTTTCAGAATTGGTTATCAGTAAGATAAACTATTTAGGAAAAAAGTCTGATGAATTTAATGCCTGTGGGAAATTGTTACTCAATATTAAGCATGATGAAACTCATACTCAAGAGAAAAATGAAGTTTTGAAAAATAGGAACACACTGAGTCATCATGAGGAGACTTTGCAGCATGAGAAGATTCAAACTTTAGAGCACAATTTTGAATACAGTATATGTCAGGAAACCCTCCTTGAAAAGGCAGTATTCAATACACAGAAGAGAGAGAACGCAGAAGAGAATAACTGTGATTATAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000189180-'6-15,'6-9,10-15
Average complexity
C2
Mappability confidence:
93%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.061 A=0.000 C2=0.074
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NO
C2:
PF134651=zf-H2C2_2=WD(100=3.4),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.4),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF079757=C1_4=WD(100=8.6),PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.3),PF079757=C1_4=WD(100=5.9),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAACAAGGAGAAGAGCCA
R:
TCCACATGAATCACACTGACAGA
Band lengths:
249-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)