HsaEX0073907 @ hg38
Exon Skipping
Gene
ENSG00000198131 | ZNF544
Description
zinc finger protein 544 [Source:HGNC Symbol;Acc:HGNC:16759]
Coordinates
chr19:58243962-58263644:+
Coord C1 exon
chr19:58243962-58251384
Coord A exon
chr19:58259278-58259793
Coord C2 exon
chr19:58260851-58263644
Length
516 bp
Sequences
Splice sites
3' ss Seq
AAGTTTTTCTCTGTTTGCAGCCT
3' ss Score
7.76
5' ss Seq
GTAATCCCA
5' ss Score
-34.95
Exon sequences
Seq C1 exon
GTATTTAACTGTCTTTGAGTTAAATGTAAAGTTTTTAATAAATACCCAGAATCCATTAACTGCTGGAGGGGTAAAGTGAAGCTCTGTTGTAAAATAAAGCTGATTCCCATTATGCGTGGTCCTGTATACACAGGCTGTGGGTGACCATTATGGAACCAAAAAATACTTATTTGTTATTTTGTGCTATAGAATAGGAACTTCAGGGGTGGATACCTATGCTGTCAGGAATGCTTGTTATAAGAATTAATTAAAACACTTTGCTTAATTATTACAAAGGAAGTTATTCCATTTGTTTAGAAGAAAGCAATTAAATTGTAGAAGTATAACAATGGCTACTATTATCCAGTTTAAAGTAACTAAGCAACAAAGACACCAAGGAAAGTTGGTAGGCTTTTACTTATCTTTTGGCTGTCTTTTAAACAGGTACTTCAGGTCTTTCACAAGTCACAGGTGTAGTGGCTGATGGGAGCTTCAGGTTCCCGGTCTGGGACTTCACATAA
Seq A exon
CCTGAAGAAATGGTAGAATTGGTGCATTAAGAATATGAAGTCAGTGTTGATGTCTGAGATGCAATTATGAGATCCAGAAGTGGAACAGAAACTGATATTCTAGGACTAAGCACCAGTTAGGAGTCTGTGTTTGCTTCCTGTGGCTGCTGTAAAAAATTTCCACCAACCTGTTGGCTTAAAACAATGCAAATTTATTCTCTAAAAGTTCTGGAGGCCACAAGTCCAAAATCAATGTCACTGGATCAAAATCAAGGTGTTGATATGGTTGTGCTCCCTCTGGATGCTCCAAATGGAAAACACATTTCTGTCTTTTCCTTCTCCTGTTGGTTGCAGCATTCTTTCCAGTCTTCAGATATCTTCTGCTGTGTCTTCTCATCACCTCCTCTGTGTTTCAAATCTCCCTCTGCCTTTCTCCTATAGGAACACTTGTGATTACATTTAGAGCCCCCCTGGATAGTACAGAAAAAAAATCCCCATTTAAAAATTTTTAGCAGGGTGTGGTAGCAGGCACCTGTA
Seq C2 exon
ACTGGAAAGCTACCCTTGAGGAGAATAGGTTGAATTCTGAAAAAGATCGAGCTAGGGAAGAACTATCCCACCACGTGGAAGTGTACAGGAGTGGACCGGAGGAGCCACCCTCTTTGGTATTAGGAAAAGTGCAAGATCAGAGCAACCAGTTAAGGGAACACCAGGAGAACTCCTTGAGGTTCATGGTACTCACCTCAGAGAGACTGTTTGCTCAAAGGGAACATTGTGAGCTTGAACTTGGGGGAGGTTATTCTCTACCTTCTACTTTAAGCCTTCTACCTACAACATTACCTACAAGTACAGGTTTCCCTAAGCCCAACTCACAAGTTAAAGAGTTGAAACAAAATTCAGCTTTCATTAATCATGAGAAAAATGGAGCAGATGGGAAGCACTGTGAGAGTCATCAGTGTGCTAGAGCTTTCTGTCAGAGTATTTACTTGAGTAAACTTGGAAACGTTGAAACAGGAAAGAAAAACCCTTATGAATATATTGTCAGTGGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198131-'18-22,'18-20,21-22=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.083 A=0.800 C2=0.142
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0135222=KRAB=PD(0.1=0.0),PF134651=zf-H2C2_2=WD(100=3.8),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.1)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGGTCTGGGACTTCACATAA
R:
ACTTGTGAGTTGGGCTTAGGG
Band lengths:
349-865
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development