HsaEX0074075 @ hg19
Exon Skipping
Gene
ENSG00000172888 | ZNF621
Description
zinc finger protein 621 [Source:HGNC Symbol;Acc:24787]
Coordinates
chr3:40567270-40571807:+
Coord C1 exon
chr3:40567270-40567355
Coord A exon
chr3:40570810-40570936
Coord C2 exon
chr3:40571700-40571807
Length
127 bp
Sequences
Splice sites
3' ss Seq
GCAGGAACCTGTTGTTTCAGGAG
3' ss Score
2.62
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
CTCTTGAGGATCTTGCTTGTCCAAACCCAGAAGACAGTGCATGAAGCCAGGGGACATCCGCCATGCTCCAAACAACTTGGCCTCAG
Seq A exon
GAGTCAGTGACCTTTGAGGATGTGGCTGTTTACTTCACCCAGAATCAATGGGCCAGCCTCGACCCTGCGCAGAGGGCCCTGTACGGGGAGGTGATGCTGGAGAATTATGCAAATGTGGCTTCTCTGG
Seq C2 exon
TAGCGTTTCCATTCCCCAAACCTGCTCTGATCTCCCACCTGGAGAGAGGGGAAGCACCATGGGGCCCAGATCCCTGGGACACCGAGATTCTGAGAGGCATCAGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172888-'3-6,'3-4,5-6
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF066386=Strabismus=PU(2.0=12.5)
A:
PF0135222=KRAB=WD(100=95.3)
C2:
PF0135222=KRAB=PD(0.1=0.0)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTTGAGGATCTTGCTTGTCCA
R:
CTTGACTGATGCCTCTCAGAA
Band lengths:
194-321
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)