HsaEX0074162 @ hg19
Exon Skipping
Gene
ENSG00000251192 | ZNF674
Description
zinc finger protein 674 [Source:HGNC Symbol;Acc:17625]
Coordinates
chrX:46357162-46387880:-
Coord C1 exon
chrX:46387785-46387880
Coord A exon
chrX:46382372-46382560
Coord C2 exon
chrX:46357162-46360770
Length
189 bp
Sequences
Splice sites
3' ss Seq
TTTCTATTTCTTTGAGATAGAAA
3' ss Score
2.17
5' ss Seq
GGGGTAATT
5' ss Score
5.8
Exon sequences
Seq C1 exon
GGCATCTAGTTGGGAAGCCAGATGTGATCTTCAGGTTGGGACCAGGTGACGAGTCCTGGATGGCAGATGGAGGGACCCCGGTACGGACCTGTGCAG
Seq A exon
AAAGAAATCCTTATTGATTACTATATCTTGCATACAGAAGAGCATTTAGAACACGTGCGTACTTTTCAGAAGAAATATATAGCTAACACCTGGATAATCACCACTCAGGTTGAGAACTACGACTCTACCCCTTCCAGATGGCATCCTCCTACCTCTCTCCTGGATGTAACCTGTATCCCAAATTCGGGG
Seq C2 exon
AAGTCTGGGAAGTTGACGAGCAGATAGATCACTACAAGGAAAGCCAAGACAAATTTCTGTGGCAAGCTGCATTCATAGGCAAGGAAACACTGAAGGATGAAAGTGGTCAAGAATGTAAAATATGTAGAAAAATCATTTATCTCAACACAGACTTTGTTTCTGTAAAACAAAGACTCCCTAAATATTATTCATGGGAAAGGTGTTCAAAACATCATTTAAACTTTCTTGGTCAAAATAGAAGCTATGTAAGAAAGAAAGATGATGGATGTAAGGCATATTGGAAAGTATGCCTCCATTATAATCTTCATAAAGCTCAACCTGCAGAGAGATTTTTTGACCCTAATCAACGAGGGAAAGCCCTCCACCAAAAGCAAGCCCTTAGAAAAAGTCAGAGAAGTCAAACTGGGGAGAAACTCTACAAATGTACTGAATGTGGAAAAGTGTTTATCCAGAAAGCAAACTTAGTTGTACATCAAAGAACTCACACCGGAGAGAAACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000251192-'4-9,'4-8,10-9
Average complexity
C1*
Mappability confidence:
78%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.086 A=0.800 C2=0.139
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NA
C2:
PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=4.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTCCTGGATGGCAGATGGA
R:
TGTTTTGAACACCTTTCCCATGA
Band lengths:
257-446
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)