HsaEX0074285 @ hg19
Exon Skipping
Gene
ENSG00000185252 | ZNF74
Description
zinc finger protein 74 [Source:HGNC Symbol;Acc:13144]
Coordinates
chr22:20748405-20755048:+
Coord C1 exon
chr22:20748405-20748952
Coord A exon
chr22:20753885-20753980
Coord C2 exon
chr22:20754922-20755048
Length
96 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTCTTTTGACAGAGT
3' ss Score
9.28
5' ss Seq
CAGGTGATC
5' ss Score
4.28
Exon sequences
Seq C1 exon
TGCTGCTCTTTGTGGCAGTCGCAGTCCTTTTGTGGGAGTCCGGTCTGTCCACTTGCCGGTCCCTCAGACCGTCGGCGGTCTCTGTCCGCTTCGGGACCTGTCCGCTGGTCGCTCCGCGTCCGATGGCTCCTGGCCGCGGAACCTTAGGCCTGGCCCTGGTCTCCGAGCGCGGGTTCGCCGGGAGGAGCGTGTGGCGGGGGTGTGCCGGGGCGTGAGTGCGCCGAGCATGGGGCTGAGCCTGGTGTGGGGAGTGGGTATCTGCGGAGCCGGCCTGAACCCCACCTCAGCCGGGCGCGGGGAGGGGGCTCCGTGCGTGTGATCGTGCAGCTGTGAGCGCGTGGCCGCCCCGCGGGGCTCCGCTGCAGGCCCCTCAGCCCCAGGAGCAGTACTCGCTCTTCAGGGCCTGCCCTGGATCCTGGAGGCTACACAGCTGCCCACTCCTCCTGGGGAGGCTGCCGTGGAGGCCATGGAGATCCCTGCCCCGGAGCCCGAGAAGACAG
Seq A exon
AGTTTGGCTCTTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAACCTCCACCTCTTGGGTTCAAGCAATTCTCCTGACCTCAG
Seq C2 exon
GAATCGGTGAGTTTCAAGGATGTGGCTGTGGACTTCACCCAGGAGGAGTGGGGTCAACTAGACTCCCCTCAGAGGGCCTTGTACCGGGATGTGATGTTGGAGAACTACCAGAACCTTCTTGCCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185252_MULTIEX1-3/6=1-4
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.761 A=0.129 C2=0.345
Domain overlap (PFAM):
C1:
NO
A:
PF139001=GVQW=WD(100=83.3)
C2:
PF0135222=KRAB=WD(100=95.3)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAGTACTCGCTCTTCAGGG
R:
TAGTTGACCCCACTCCTCCTG
Band lengths:
179-275
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)