HsaEX0074285 @ hg38
Exon Skipping
Gene
ENSG00000185252 | ZNF74
Description
zinc finger protein 74 [Source:HGNC Symbol;Acc:HGNC:13144]
Coordinates
chr22:20395333-20400758:+
Coord C1 exon
chr22:20395333-20395418
Coord A exon
chr22:20399595-20399690
Coord C2 exon
chr22:20400632-20400758
Length
96 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTCTTTTGACAGAGT
3' ss Score
9.28
5' ss Seq
CAGGTGATC
5' ss Score
4.28
Exon sequences
Seq C1 exon
CTCTTTCCTCTCAGGATCCTGCTCTTTCCCTGAAAGAGAATCTCGAGGATATATCGGGTTGGGGTCTTCCCGAAGCCAGGTCCAAG
Seq A exon
AGTTTGGCTCTTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAACCTCCACCTCTTGGGTTCAAGCAATTCTCCTGACCTCAG
Seq C2 exon
GAATCGGTGAGTTTCAAGGATGTGGCTGTGGACTTCACCCAGGAGGAGTGGGGTCAACTAGACTCCCCTCAGAGGGCCTTGTACCGGGATGTGATGTTGGAGAACTACCAGAACCTTCTTGCCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185252_MULTIEX1-3/6=2-4
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.457 A=0.103 C2=0.344
Domain overlap (PFAM):
C1:
NO
A:
PF139001=GVQW=WD(100=83.3)
C2:
PF0135222=KRAB=WD(100=95.3)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGATCCTGCTCTTTCCCTGA
R:
CATCACATCCCGGTACAAGGC
Band lengths:
170-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development