HsaEX1006954 @ hg38
Exon Skipping
Gene
ENSG00000203697 | CAPN8
Description
calpain 8 [Source:HGNC Symbol;Acc:HGNC:1485]
Coordinates
chr1:223615970-223619453:-
Coord C1 exon
chr1:223619293-223619453
Coord A exon
chr1:223616323-223616488
Coord C2 exon
chr1:223615970-223616145
Length
166 bp
Sequences
Splice sites
3' ss Seq
GAGAGCAAGGTGATGTTAAGTCT
3' ss Score
-11.47
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
GATGTCACTTTCAGATTTCGTGAGGCAGTTCTCTCGGTTGGAGATCTGCAACCTGTCCCCGGACTCTCTGAGTAGCGAGGAGGTGCACAAATGGAACCTGGTCCTGTTCAACGGCCACTGGACCCGGGGCTCCACAGCTGGGGGCTGCCAGAACTACCCAG
Seq A exon
TCTTTCCCCAGGAAGACTTGGAGGCAGTGCTGCCCAGTGTAGCCCTCGGATCATGGGATCCTGAATATTCCCAGTCAAGCACTTCTGGGCTCCTCGTTGATCAAATGGACAAGCACACATTTCCAAATGCGATGCCATATGTCTGTGTGTGTGGATGTGTAGGAAG
Seq C2 exon
CCACGTACTGGACCAATCCCCAGTTCAAAATCCGTTTGGATGAAGTGGATGAGGACCAGGAGGAGAGCATCGGTGAACCCTGCTGTACAGTGCTGCTGGGCCTGATGCAGAAAAATCGCAGGTGGCGGAAGCGGATAGGACAAGGCATGCTTAGCATCGGCTATGCCGTCTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000203697_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.058 A=0.018 C2=0.023
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=PD(6.3=34.5),PF0106717=Calpain_III=PU(15.2=43.6)
A:
PF0106717=Calpain_III=PD(16.7=8.9)
C2:
PF0106717=Calpain_III=FE(36.7=100)
Main Inclusion Isoform:
ENST00000366872fB11306
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCCCGGACTCTCTGAGTAG
R:
CATGCCTTGTCCTATCCGCTT
Band lengths:
256-422
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains