HsaEX1007839 @ hg38
Exon Skipping
Gene
ENSG00000143776 | CDC42BPA
Description
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
Coordinates
chr1:227139576-227143024:-
Coord C1 exon
chr1:227142945-227143024
Coord A exon
chr1:227141478-227141614
Coord C2 exon
chr1:227139576-227139742
Length
137 bp
Sequences
Splice sites
3' ss Seq
TCTGTCATCCTCACTTTCAGCTT
3' ss Score
9.61
5' ss Seq
CTAGTAAGG
5' ss Score
5.17
Exon sequences
Seq C1 exon
GAAACGATGCCCCCACCAACACATACTGCATTTTCTGGCCACCATCTGCCATTTGTTGGTTTTACATATACTAGTAGCTG
Seq A exon
CTTGCATCTCCTTTCACTGAAAGGATTGAGGCAAACCGCAGACAACTTCCACAAGCTCCAGTTACCATATTTACCGCCTACTTACTGTTAGACCCAAATTCTCTGTTCTTTTCATGGATGAACTGTGCAAGCCTCTA
Seq C2 exon
TGTACTTTCTGATCGGAGCTGTTTAAGAGTTACGGCTGGTCCCACCTCACTGGATCTTGATGTTAATGTTCAGAGGACTCTAGACAACAACTTAGCAACTGAAGCTTATGAAAGAAGAATTAAGCGCCTTGAGCAAGAAAAACTTGAACTCAGTAGAAAACTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143776_MULTIEX6-4/4=3-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.355 A=0.000 C2=0.129
Domain overlap (PFAM):
C1:
PF0043319=Pkinase_C=PD(53.2=92.6)
A:
NO
C2:
PF0157614=Myosin_tail_1=PU(12.2=70.2)
Main Inclusion Isoform:
ENST00000334218fB11812
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGCCCCCACCAACACATAC
R:
CTTGAAGTTTTCTACTGAGTTCAAGT
Band lengths:
242-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains