HsaEX1008160 @ hg38
Exon Skipping
Gene
ENSG00000219073 | CELA3B
Description
chymotrypsin like elastase family member 3B [Source:HGNC Symbol;Acc:HGNC:15945]
Coordinates
chr1:21986531-21998642:+
Coord C1 exon
chr1:21986531-21986683
Coord A exon
chr1:21989262-21989579
Coord C2 exon
chr1:21998151-21998642
Length
318 bp
Sequences
Splice sites
3' ss Seq
TGCCCCCCCAACTTTTCCAGACC
3' ss Score
8.52
5' ss Seq
AAGGTACCA
5' ss Score
7.87
Exon sequences
Seq C1 exon
GGTGACTCTGGAGGACCCCTCAACTGCCCCACAGAGGATGGTGGCTGGCAGGTCCATGGCGTGACCAGCTTTGTTTCTGCCTTTGGCTGCAACACCCGCAGGAAGCCCACGGTGTTCACTCGAGTCTCCGCCTTCATTGACTGGATTGAGGAG
Seq A exon
ACCATAGCAAGCCACTAGAACCAAGGCCCAGCTGGCAGTGCTGATCGATCCCACATCCTGAATAAAGAATAAAGATCTCTCAGAAAATTCCAAGTTGAATCTTTCTTTCTTTGTTGACTCACCTCTTCCCCTCTGGCCTGTTCCTAAAATCTTAGATCTCATATGCAGAGACAGGACCAGGTCCAACCCTTTCATACGAAGATGAGGGAAAAATGATGCTGGGAGAGAAGGGAGTTGCTGTGCGGTGACCTGACCATCCTGGTTTGCCTGGAACTTCAGGAGTGAAGACACTGGACATTTAATGCTAAAACTGGGAAG
Seq C2 exon
AAACTACAGGGCAACAAGGCACCAGAGTCCCGGACTTAGGACCACTGTGTGTGATTCACCGTGAACACTGGCATATTAAAGGCTCTGAGAAGTCCTGTAGGAAAGGACAATTTGAACTTTGTTTGAGCTCATATTTTCCAATCCCATCTGACCTTTAGTTCTTCACTGAGTGCCCACTGGGTTATATTCTGGGAGCCGAGGCCACAGCAGTGAACAAAGCACACAAAACCCCCCGCCCCATGGGGGCTCCGTTCTAGTGGGTCCATTTATCATCAAACATCTATTAATATCTCTAGAATGTGCCCATCAGGACACCATCCAGATGCTGCTGCGCTTTTCCAGGCCACACAGAGGGGACACCCTCCAGGTGCATCCTGCATGAATATCAGGCTCAACCGTGCTTTCAGGGTAGGAAGCGGAGGGCATTTGAAGAGTCCTTTCCCTTCCTTCATTCATTTGTTGTCTCCTTGAATAAATGCTGTTGAAAACCTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000219073_MULTIEX1-2/3=C1-C2
Average complexity
ME(2-3[96=100])
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.027 A=0.000 C2=0.583
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PD(20.4=94.1)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000400277fB12012
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTCCGCCTTCATTGACTGG
R:
TCTGGATGGTGTCCTGATGGG
Band lengths:
353-671
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains