HsaEX1010853 @ hg38
Exon Skipping
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]
Coordinates
chr19:40991299-41002693:+
Coord C1 exon
chr19:40991299-40991476
Coord A exon
chr19:40995720-40995851
Coord C2 exon
chr19:41002593-41002693
Length
132 bp
Sequences
Splice sites
3' ss Seq
TATCTATGTCTTTCCAGTAGGAG
3' ss Score
6.74
5' ss Seq
AAGGTTCAG
5' ss Score
2.52
Exon sequences
Seq C1 exon
CAGGACCATGGAACTCAGCGTCCTCCTCTTCCTTGCACTCCTCACAGGACTCTTGCTACTCCTGGTTCAGCGCCACCCTAACACCCATGACCGCCTCCCACCAGGGCCCCGCCCTCTGCCCCTTTTGGGAAACCTTCTGCAGATGGATAGAAGAGGCCTACTCAAATCCTTTCTGAGG
Seq A exon
GAGTGGATCTGATTGCCATCAATCAATAATACCTGAGACCAAGGGACTCCAATCAATTCAGCATGCTTTGCCTAATGATATTTGTTTGTAATACTGTTGCGGGACAATCAAAGACTGGAGAGACCAAAAAAG
Seq C2 exon
GCTGGAGTGCAGTGGCACTATCTCGCCTCACTGCAACCTCCGCCTCCCCGGGCTCAAGCAATTCTCTCGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408-'0-1,'0-0,1-1
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.105 A=0.000 C2=NA
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(18.7=45.6)
A:
NO
C2:
NA
Main Inclusion Isoform:
ENST00000324071fB13357
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCTTGCACTCCTCACAGGA
R:
GTAGTCCCAGCTACTCGGGAG
Band lengths:
247-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains