HsaEX1011329 @ hg38
Exon Skipping
Gene
ENSG00000140995 | DEF8
Description
differentially expressed in FDCP 8 homolog [Source:HGNC Symbol;Acc:HGNC:25969]
Coordinates
chr16:89949417-89954376:+
Coord C1 exon
chr16:89949417-89949513
Coord A exon
chr16:89953758-89953819
Coord C2 exon
chr16:89954243-89954376
Length
62 bp
Sequences
Splice sites
3' ss Seq
GACAGGGGCTGTGGTTTCAGGGT
3' ss Score
3.59
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
Exon sequences
Seq C1 exon
CAGGTGCCGAACCCACGGCCAGGCTTCCGTGGCCAGCAGCCCTAGAGGAATGGCCATCCTGTCCCTGCGAGCCCCTGGGCCCTGGCAGGCGATGCAG
Seq A exon
GGTGCTCTGACAAGAAAGCACCTTTGCTTGGGGCCCAGGAAGGAGGAACCCATTTCTGAGAG
Seq C2 exon
GTGGGATGCTATGGAATATGATGAGAAGCTGGCCCGTTTCCGGCAGGCCCACCTCAACCCCTTCAACAAGCAGTCTGGGCCGAGACAGCATGAGCAGGGCCCTGGGGAGGAGGTCCCGGACGTCACTCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140995_MULTIEX1-5/6=1-6
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.488 A=0.810 C2=0.748
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000566079fB13610
Other Inclusion Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTAGAGGAATGGCCATCCT
R:
CCAGACTGCTTGTTGAAGGGG
Band lengths:
136-198
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains