HsaEX1011938 @ hg38
Exon Skipping
Gene
ENSG00000115423 | DNAH6
Description
dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]
Coordinates
chr2:84677005-84681528:+
Coord C1 exon
chr2:84677005-84677136
Coord A exon
chr2:84678991-84679094
Coord C2 exon
chr2:84681357-84681528
Length
104 bp
Sequences
Splice sites
3' ss Seq
TTCATCACATCCCACCTTAGCAG
3' ss Score
3.29
5' ss Seq
AAAGTAAAT
5' ss Score
4.06
Exon sequences
Seq C1 exon
GATGTAACAATCATATCGGCATGTGCACCTCCAGGCGGTGGCCGCAACCCTGTGACTCCCCGCTTCATCAGACACTTCAGCATGCTGTGCCTCCCAATGCCCTCAGAGCACAGTCTGAAACAGATTTTTCAG
Seq A exon
CAGGACCCAAGAATTCATCACCCGTCTGTCCTGTCCTTCATTACTGTTTGGAGGAAAAAGAACTTGGATATAATCAAGAATTGAAGAAGAGCAAAATCAATAAA
Seq C2 exon
GCCATCTTAAATGGTTTCCTGAGTGACTTTCCACCAGCTGTAAAGCAAACTGCATCAAGCATTGTAGAAGCCTCAGTTGAGATTTATAACAAAATGAGTGTTGACCTCCTGCCAACACCCGCCAAGTCCCATTATGTCTTTAACTTGAGGGACTTATCCAAATGTGTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115423_MULTIEX3-2/5=1-3
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.003 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127752=AAA_7=FE(15.8=100)
A:
PF127752=AAA_7=PD(9.4=71.4)
C2:
PF127752=AAA_7=FE(21.0=100)
Main Inclusion Isoform:
ENST00000389394fB13996
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATATCGGCATGTGCACCTC
R:
CATAATGGGACTTGGCGGGTG
Band lengths:
258-362
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains