HsaEX1012089 @ hg38
Exon Skipping
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:171841500-171921821:+
Coord C1 exon
chr1:171841500-171841817
Coord A exon
chr1:171858472-171858636
Coord C2 exon
chr1:171921748-171921821
Length
165 bp
Sequences
Splice sites
3' ss Seq
CTCTCACTGTCTAAATGCAGGAA
3' ss Score
8.13
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
AGCCAAGCGGCGGGCTGGCGGCGGGCTCCGACGTCTGCGCCAGGACCTGGCTGGCTGAGCCCGGCGCAGCAGCAGCAGCCAGGGCAGCGCGGCCCCTACTCCCTGTCAGGTCGTAGAGGCGAGCAGGGACCAGCTGGTCGCCGGCCCCTCGGGCAAGATGGGGAACCGGGAGATGGAGGAGCTGATCCCGCTGGTGAACCGTCTGCAGGACGCGTTTTCGGCGCTGGGACAGAGCTGCCTGCTGGAGCTGCCGCAGATCGCCGTGGTGGGCGGCCAGAGCGCCGGCAAGAGCTCGGTGCTCGAGAACTTCGTGGGCAG
Seq A exon
GAACCAAATGGATTTGAAAAAAAGGATTATGATACTGAAAAGATTGGTCCATCCCAGCATCTCCCAAAGCAAGTATATGGATATCTGTGTAAGATTTACCTGAGGAACTTATGAAATAAAGGTTCCTAAGCTCCACTAATGGAGGCCCACTCAGTGGGTCTGGAG
Seq C2 exon
GGACTTTCTCCCTCGAGGGTCGGGCATTGTAACAAGACGACCTCTTGTGCTGCAGCTTGTTACTTCTAAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959_MULTIEX1-1/2=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0035018=Dynamin_N=PU(11.5=37.0)
A:
PF0035018=Dynamin_N=PD(44.7=48.6)
C2:
PF0035018=Dynamin_N=FE(14.4=100)
Main Inclusion Isoform:
ENST00000355305fB14092
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCTGTCAGGTCGTAGAGG
R:
CTTGTTACAATGCCCGACCCT
Band lengths:
256-421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains