HsaEX1022370 @ hg38
Exon Skipping
Gene
ENSG00000148356 | LRSAM1
Description
leucine rich repeat and sterile alpha motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25135]
Coordinates
chr9:127461173-127462373:+
Coord C1 exon
chr9:127461173-127461257
Coord A exon
chr9:127461613-127462024
Coord C2 exon
chr9:127462252-127462373
Length
412 bp
Sequences
Splice sites
3' ss Seq
AGCAGTGCTTCCACCTCCAGCGA
3' ss Score
5.95
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GTCTTAAACGTGGAAAGGAATCAACTGATGCAGCTCCCACGTTCCATTGGGAACCTGACCCAGCTCCAGACTCTCAATGTTAAAG
Seq A exon
CGACGCACCAAGCCTCCTGAGGAGTCCACTGGGCAGGCTGAGGGCAGTGGTGCCATCCCCAGTTTACACACGAGGAAAACAAGGCCCGGGAAATCAAGTGTGACTTGCTCAAGACCACCCCGTGGGATGGTGACAGAGCCAAGACCACTGCACAGGCGCCTTACCCGCAGGAGCGCTCTGCTCGCCACACCCAGCTCTCTCCCTTCTCCTGGCTGTCCTTAAGCACTTCCTGCAGAGTGCCTCTGTTTATCAACTGTAACATATGAGTAATGAGAACAACAGTGGCGCCCCATTGCTCAGCCATTACAGCATGAGGGGCCCTGTGCGGAGGACCTCACACATCATCTACCTGAACCTCCAATCTCCCCGTGTTCTTATAAGGCTGGGTGGCAGTGTCATCCCCATTTTCCAG
Seq C2 exon
ACAACAAGCTGAAGGAGCTTCCAGACACCGTGGGGGAGCTTCGAAGCCTGCGTACCCTCAACATCAGTGGAAACGAGATCCAGAGATTGCCGCAGATGCTGGCTCACGTTCGAACCCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148356_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127992=LRR_4=PD(40.4=65.5),PF127992=LRR_4=PU(20.0=31.0)
A:
NO
C2:
PF127992=LRR_4=PD(77.8=85.4)
Main Inclusion Isoform:
ENST00000300417fB19169
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTTAAACGTGGAAAGGAATCA
R:
CTCCAGGGTTCGAACGTGAG
Band lengths:
207-619
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains