HsaEX1022774 @ hg38
Exon Skipping
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]
Coordinates
chr17:69505780-69516903:+
Coord C1 exon
chr17:69505780-69505846
Coord A exon
chr17:69509867-69509969
Coord C2 exon
chr17:69516855-69516903
Length
103 bp
Sequences
Splice sites
3' ss Seq
TTTTTGTTTTTTTGAGACAGGGT
3' ss Score
3.67
5' ss Seq
AAAGTAGGT
5' ss Score
6.84
Exon sequences
Seq C1 exon
GCAAGAAGCGAAACCCTGGCCTTAAAATTCCAAAAGAAGCATTTGAACAACCTCAGACCAGTTCCAC
Seq A exon
GGTCTCACTCTGTCACCCAGGCTGGAGTGCAGAGGTGTGATCATGGCTCACTGCAGTCTCAGCCTCCCCTGGCTCAAGTGATCCTCCCATCTCAGCCTCCAAA
Seq C2 exon
ACCACCTCGAGATTTAGACTCCAAGGCTTGCATTTCTATTGGAAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984-'11-17,'11-16,12-17
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.986 A=0.538 C2=0.682
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCGAAACCCTGGCCTTAA
R:
TCCAATAGAAATGCAAGCCTTGGA
Band lengths:
106-209
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains