HsaEX1025937 @ hg38
Exon Skipping
Gene
ENSG00000163072 | NOSTRIN
Description
nitric oxide synthase trafficking [Source:HGNC Symbol;Acc:HGNC:20203]
Coordinates
chr2:168842992-168851182:+
Coord C1 exon
chr2:168842992-168843117
Coord A exon
chr2:168846796-168846951
Coord C2 exon
chr2:168851084-168851182
Length
156 bp
Sequences
Splice sites
3' ss Seq
GTTCCTCCTCTAAATCCCAGAAC
3' ss Score
6.12
5' ss Seq
AAGGTAATT
5' ss Score
8.83
Exon sequences
Seq C1 exon
CTCCTCAATAAACTGACAAAATCAACTGAAAAGTTGGAAAAGGAAGATGAAAATTACTACCAAAAAAACATGGCGGGTTATTCTACCAGACTGAAATGGGAAAACACACTAGAGAACTGCTACCAG
Seq A exon
AACACAGAAAATGATTCGAGTGGCTGCTTTCTCAGTTCTCCCAAGGATGGCACTTGAGTAGTCCCACTCTAGATGAGACGAATGACAACTCATTACATAAAATGGACGCCTCAGGACAGTAGGGCTTCATTCTTTCCTAGGACTCTGTTGAAAAAG
Seq C2 exon
AGCATTCTGGAGCTGGAGAAGGAAAGAATTCAACTTTTATGCAATAACTTAAACCAGTACAGCCAACATATTTCTCTTTTTGGCCAAACCCTGACCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000163072_MULTIEX3-1/2=C1-C2
Average complexity
ME(1-2[95=100])
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.117 A=0.333 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000317647fB21283
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTCAATAAACTGACAAAATCAACT
R:
TCAGGGTTTGGCCAAAAAGAGA
Band lengths:
219-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains