HsaEX1027174 @ hg38
Exon Skipping
Gene
ENSG00000167081 | PBX3
Description
PBX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:8634]
Coordinates
chr9:125748550-125915927:+
Coord C1 exon
chr9:125748550-125748623
Coord A exon
chr9:125797395-125797465
Coord C2 exon
chr9:125915686-125915927
Length
71 bp
Sequences
Splice sites
3' ss Seq
GAACTTACTTTACTTTTCAGAAT
3' ss Score
8.04
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GAAACATGCCCTGAACTGTCACAGAATGAAACCAGCGCTCTTCAGCGTCCTGTGTGAGATCAAAGAGAAAACAG
Seq A exon
AATGTCCTCATTTAAACTTTTTTTTAACAACTCATGGATTTGGTCTCTGAGTTACTTTACCTCTACTCAAG
Seq C2 exon
GTCTCAGCATCAGAGGAGCCCAGGAGGAGGACCCTCCCGATCCCCAGCTAATGAGACTGGACAATATGCTTTTGGCAGAAGGGGTTTCAGGTCCTGAGAAAGGTGGGGGATCGGCGGCAGCAGCTGCAGCCGCGGCAGCCTCTGGAGGTTCTTCAGATAACTCTATTGAACACTCAGATTACAGAGCCAAATTGACCCAGATCAGACAAATCTATCACACAGAACTGGAGAAATATGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167081_MULTIEX1-3/6=C1-5
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.152 A=0.000 C2=0.687
Domain overlap (PFAM):
C1:
PF037928=PBC=PU(10.1=94.1)
A:
NA
C2:
PF037928=PBC=FE(50.3=100),PF070286=DUF1319=PU(41.8=46.9),PF040917=Sec15=PU(34.6=34.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATGCCCTGAACTGTCACAG
R:
TCAGGACCTGAAACCCCTTCT
Band lengths:
168-239
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains