HsaEX1029721 @ hg38
Exon Skipping
Gene
ENSG00000253649 | PRSS51
Description
protease, serine 51 [Source:HGNC Symbol;Acc:HGNC:37321]
Coordinates
chr8:10497712-10498808:-
Coord C1 exon
chr8:10498728-10498808
Coord A exon
chr8:10497884-10497971
Coord C2 exon
chr8:10497712-10497772
Length
88 bp
Sequences
Splice sites
3' ss Seq
TTTTTATATTCGTTCTTTAGATT
3' ss Score
9.39
5' ss Seq
AAGGTCATT
5' ss Score
4.32
Exon sequences
Seq C1 exon
AAAACGTACAATGTGGCCACAGGCCTGCTTTTCCAAACTCGTCATGGTTACCATTTCATGAACGGCTTCAAGTCCAGAATG
Seq A exon
ATTAGACATGGCCGTGGTAAATGTCACTGTGGTCATGGGAACGAGAACATTCAGCAACATCCACTCGGAGAGAAAGCAAGTGCAGAAG
Seq C2 exon
GAGGAGGAGAGGACCTGGGACTGGTGTTGGATGGCACAGTGGGTAACGACCAATGGGTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000253649_MULTIEX1-1/3=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.046 A=0.107 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(53.7=67.7)
A:
PF0008921=Trypsin=FE(35.4=100)
C2:
PF0008921=Trypsin=PD(8.5=33.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACGTACAATGTGGCCACAGG
R:
CCCATTGGTCGTTACCCACTG
Band lengths:
136-224
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains