HsaEX1029727 @ hg38
Exon Skipping
Gene
ENSG00000237412 | PRSS56
Description
protease, serine 56 [Source:HGNC Symbol;Acc:HGNC:39433]
Coordinates
chr2:232522515-232523202:+
Coord C1 exon
chr2:232522515-232522614
Coord A exon
chr2:232522744-232522861
Coord C2 exon
chr2:232523060-232523202
Length
118 bp
Sequences
Splice sites
3' ss Seq
ACGACCTGGCCCTGGTGCAGCTG
3' ss Score
4.68
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
CGCCCCGAATGAGCTTCTGTGGACTGTGACGCTGGCAGAGGGGTCCCGGGGGGAGCAAGCGGAGGAGGTGCCAGTGAACCGCATCCTGCCCCACCCCAAG
Seq A exon
CTGTGGACGCCGGTGAGCCCGGGGGGATCGGCGCGCCCCGTGTGCCTGCCCCAGGAGCCCCAGGAGCCCCCTGCCGGAACCGCCTGCGCCATCGCGGGCTGGGGCGCCCTCTTCGAAG
Seq C2 exon
ACGGGCCTGAGGCTGAAGCAGTGAGAGAGGCCCGTGTTCCCCTGCTCAGCACCGACACCTGCCGAAGAGCCCTGGGGCCCGGGCTGCGCCCCAGCACCATGCTCTGCGCCGGGTACCTGGCGGGGGGCGTTGACTCGTGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000237412-'6-8,'6-7,7-8
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.412 A=0.185 C2=0.083
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(14.5=100)
A:
PF0008921=Trypsin=FE(23.2=100)
C2:
PF0008921=Trypsin=FE(20.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCCGAATGAGCTTCTGTG
R:
CTGGCACGAGTCAACGCC
Band lengths:
242-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains