HsaEX1036266 @ hg38
Exon Skipping
Gene
ENSG00000146197 | SCUBE3
Description
signal peptide, CUB domain and EGF like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:13655]
Coordinates
chr6:35214419-35227702:+
Coord C1 exon
chr6:35214419-35214503
Coord A exon
chr6:35218126-35218198
Coord C2 exon
chr6:35227580-35227702
Length
73 bp
Sequences
Splice sites
3' ss Seq
TTGTTTTTTGAAACCTTCAGGAA
3' ss Score
7.63
5' ss Seq
GGTGTGAGT
5' ss Score
6.05
Exon sequences
Seq C1 exon
ATGGGCTCGGGGCGCGTACCCGGGCTCTGCCTGCTTGTCCTGCTGGTCCACGCCCGCGCCGCCCAGTACAGCAAAGCCGCGCAAG
Seq A exon
GAATCTGAGAGCATGAGAACCGGTTTGAGATGTGAGCAGCTGGGACCTGTTGTAAGAGGAGCCGGCCCTGGGT
Seq C2 exon
ATGTGGATGAGTGTGTGGAGGGGACTGACAACTGCCACATCGATGCTATCTGCCAGAACACCCCGAGGTCATACAAGTGCATCTGCAAGTCTGGCTACACAGGGGACGGCAAACACTGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146197_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=67=67%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF129472=EGF_3=WD(100=85.7)
Main Inclusion Isoform:
ENST00000274938fB25296
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTGCCTGCTTGTCCTGC
R:
TCCCCTGTGTAGCCAGACTTG
Band lengths:
167-240
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains