HsaEX6015424 @ hg19
Exon Skipping
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128388781-128389976:+
Coord C1 exon
chr2:128388781-128388938
Coord A exon
chr2:128389175-128389328
Coord C2 exon
chr2:128389821-128389976
Length
154 bp
Sequences
Splice sites
3' ss Seq
GTGCTCCTTGACAGCCACACCCA
3' ss Score
-10.25
5' ss Seq
CAGGTCTGC
5' ss Score
5.61
Exon sequences
Seq C1 exon
GGCTCCAGAGAAGGACATGGTGAGCATGGCCGTGCTGCCCCTGGCCCGTGCCCGTGGCCACCTGTGGGCCTATTCCTGCGAGCCGCTGCGACAGCCGCTGCTCAAGCGAGTCCACGCCAACGTCGACCTCTGGGACATCGCCTGCCAGATCTTTGTCG
Seq A exon
CCATCCTCCGGTACATGGGCGACTACCCTTCTCGGCAGGCCTGGCCCACCCTGGAGCTCACCGACCAGATCTTCACACTGGCCCTGCAGCACCCGGCCCTCCAGGACGAGGTCTACTGCCAGATCCTGAAGCAGCTGACGCACAACTCCAACAG
Seq C2 exon
GCACAGCGAAGAGCGGGGCTGGCAGCTGCTGTGGCTGTGCACGGGCCTCTTCCCGCCCAGCAAGGGGCTGCTGCCCCATGCCCAGAAGTTTATAGACACTCGGAGGGGGAAGCTGCTGGCCCCCGACTGCAGCCGCCGAATCCAGAAGGTCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-'45-51,'45-50,46-51=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.057
Domain overlap (PFAM):
C1:
NO
A:
PF0078412=MyTH4=PU(34.0=69.2)
C2:
PF0078412=MyTH4=FE(49.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTCCAGAGAAGGACATGGT
R:
ATAAACTTCTGGGCATGGGGC
Band lengths:
251-405
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)