HsaEX6015733 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141641386-141660734:-
Coord C1 exon
chr2:141660489-141660734
Coord A exon
chr2:141643707-141643904
Coord C2 exon
chr2:141641386-141641590
Length
198 bp
Sequences
Splice sites
3' ss Seq
AAAAATAAATTTAATTTCAGATC
3' ss Score
5.76
5' ss Seq
GAGGTACAT
5' ss Score
6.75
Exon sequences
Seq C1 exon
ATGAGTGTTCGCTGAACAATGGAGGCTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCTGAAGGACTTCAACTCAACAAAGACAATAAAACATGTGAAATTGTGGATTATTGTAGCAATCATCTAAAGTGCAGCCAAGTATGTGAGCAGCACAAGCACACAGTCAAGTGCTCATGTTATGAAGGTTGGAAGCTGGATGTAGACGGTGAAAGTTGTACAAGTGTTG
Seq A exon
ATCCTTTTGAAGCATTCATCATCTTTTCTATTCGTCATGAGATCAGAAGGATTGATCTTCACAAAAGAGACTATAGTCTACTTGTTCCTGGATTGAGAAACACAATAGCACTTGATTTTCACTTCAATCAAAGTTTACTTTATTGGACAGATGTTGTAGAAGACAGAATATACCGGGGAAAGCTTTCTGAAAGTGGAG
Seq C2 exon
GTGTCAGTGCCATTGAAGTGGTTGTGGAGCATGGCCTGGCTACTCCAGAAGGCCTGACAGTCGACTGGATAGCAGGAAACATATACTGGATAGACAGCAATCTGGACCAAATCGAAGTGGCCAAACTAGATGGCTCCCTAAGAACTACACTAATAGCAGGAGCCATGGAACACCCCAGGGCCATTGCTTTGGACCCAAGATATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'23-24,'23-23,24-24=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(4.8=2.4),PF146701=FXa_inhibition=WD(100=44.6),PF146701=FXa_inhibition=WD(100=42.2)
A:
PF0005812=Ldl_recept_b=PU(48.9=32.8)
C2:
PF0005812=Ldl_recept_b=PD(48.9=31.9),PF0005812=Ldl_recept_b=WD(100=59.4),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCTGCCCTGAAGGACTTCA
R:
TATCCAGTCGACTGTCAGGCC
Band lengths:
247-445
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)