HsaEX6027104 @ hg19
Exon Skipping
Gene
ENSG00000100197 | CYP2D6
Description
cytochrome P450, family 2, subfamily D, polypeptide 6 [Source:HGNC Symbol;Acc:2625]
Coordinates
chr22:42522853-42523936:-
Coord C1 exon
chr22:42523844-42523936
Coord A exon
chr22:42523449-42523636
Coord C2 exon
chr22:42522853-42522994
Length
188 bp
Sequences
Splice sites
3' ss Seq
GGGGACGCATGTCTGTCCAGGCC
3' ss Score
3.48
5' ss Seq
AAGGTAGGC
5' ss Score
10.08
Exon sequences
Seq C1 exon
TGGTGGCTGACCTGTTCTCTGCCGGGATGGTGACCACCTCGACCACGCTGGCCTGGGGCCTCCTGCTCATGATCCTACATCCGGATGTGCAGC
Seq A exon
GCCGTGTCCAACAGGAGATCGACGACGTGATAGGGCAGGTGCGGCGACCAGAGATGGGTGACCAGGCTCACATGCCCTACACCACTGCCGTGATTCATGAGGTGCAGCGCTTTGGGGACATCGTCCCCCTGGGTGTGACCCATATGACATCCCGTGACATCGAAGTACAGGGCTTCCGCATCCCTAAG
Seq C2 exon
GGAACGACACTCATCACCAACCTGTCATCGGTGCTGAAGGATGAGGCCGTCTGGGAGAAGCCCTTCCGCTTCCACCCCGAACACTTCCTGGATGCCCAGGGCCACTTTGTGAAGCCGGAGGCCTTCCTGCCTTTCTCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100197-'10-15,'10-14,12-15=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.018 A=0.099 C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(14.2=100)
A:
PF0006717=p450=FE(18.8=100)
C2:
PF0006717=p450=FE(14.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTGGCTGACCTGTTCTCTG
R:
TGCTGAGAAAGGCAGGAAGGC
Band lengths:
234-422
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)