HsaEX6036986 @ hg38
Exon Skipping
Gene
ENSG00000185842 | DNAH14
Description
dynein axonemal heavy chain 14 [Source:HGNC Symbol;Acc:HGNC:2945]
Coordinates
chr1:225389734-225398666:+
Coord C1 exon
chr1:225389734-225389873
Coord A exon
chr1:225392291-225392451
Coord C2 exon
chr1:225398520-225398666
Length
161 bp
Sequences
Splice sites
3' ss Seq
GTGTGTGTTCTTCTCCAAAGCCT
3' ss Score
8.25
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
GTATATGAGATTTGTCACAGTTTGGAAGCAGTCTATTCCATCAACTAGCCAAAAATGCAAACACCCTGAGGATTCAGAGAACAATTTCTTTGAAGGGTTTCCTTCAAGATACTGGCTCCCAGCTTTCTTCTTTCCACAAG
Seq A exon
CCTTTCTTGCTGCTGTGCTTCAAGACTATGGGAGGTCCCGAGGAATCGCTGTGGATGCCCTCACCTTCACCCACCATGTGATTTCCAACACCACTGACAAGGATGAGAAGTTCTCCGTATTTATGCCAAAGAAACTCAACATAGTCAGGAGAGCGTTTAAG
Seq C2 exon
GGCTCAGCTTCCTCTCACACTGGAGTTTACATTTTTGGTTTATTCATCGAGGGGGCAAGATGGAATCGTGAACAGAAAATACTGGAAGACTCGCTGCCTCTGGAGATGTGCTGTGATTTTCCCGACATATACTTTTTGCCAACAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185842-'140-187,'140-184,141-187=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=PD(2.2=10.4),PF0302810=Dynein_heavy=PU(16.7=70.8)
A:
PF0302810=Dynein_heavy=FE(26.2=100)
C2:
PF0302810=Dynein_heavy=FE(23.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCACAGTTTGGAAGCAGTCT
R:
TGTCGGGAAAATCACAGCACA
Band lengths:
255-416
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains