HsaEX6046136 @ hg19
Exon Skipping
Gene
ENSG00000204592 | HLA-E
Description
major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:4962]
Coordinates
chr6:30458914-30460213:+
Coord C1 exon
chr6:30458914-30459189
Coord A exon
chr6:30459314-30459430
Coord C2 exon
chr6:30460181-30460213
Length
117 bp
Sequences
Splice sites
3' ss Seq
ACGTTCCCCTCTTTTCCCAGAGC
3' ss Score
10.09
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
AGCCCCCAAAGACACACGTGACTCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCAGGATGGGGAGGGCCATACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCAGGGGATGGAACCTTCCAGAAGTGGGCAGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACGTGCCATGTGCAGCATGAGGGGCTACCCGAGCCCGTCACCCTGAGATGGA
Seq A exon
AGCCGGCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGATCTGTGGTCTCTGGAGCTGTGGTTGCTGCTGTGATATGGAGGAAGAAGAGCTCAG
Seq C2 exon
GTGGAAAAGGAGGGAGCTACTCTAAGGCTGAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204592-'7-6,'7-5,8-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.387 A=0.000 C2=0.667
Domain overlap (PFAM):
C1:
PF0765410=C1-set=WD(100=92.5)
A:
PF066236=MHC_I_C=PU(8.0=5.0)
C2:
PF066236=MHC_I_C=FE(44.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCATGAGGCCACCCTGAG
R:
AGTAGCTCCCTCCTTTTCCAC
Band lengths:
258-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)