HsaEX6046136 @ hg38
Exon Skipping
Gene
ENSG00000204592 | HLA-E
Description
major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962]
Coordinates
chr6:30491137-30492436:+
Coord C1 exon
chr6:30491137-30491412
Coord A exon
chr6:30491537-30491653
Coord C2 exon
chr6:30492404-30492436
Length
117 bp
Sequences
Splice sites
3' ss Seq
ACGTTCCCCTCTTTTCCCAGAGC
3' ss Score
10.09
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
AGCCCCCAAAGACACACGTGACTCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCAGGATGGGGAGGGCCATACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCAGGGGATGGAACCTTCCAGAAGTGGGCAGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACGTGCCATGTGCAGCATGAGGGGCTACCCGAGCCCGTCACCCTGAGATGGA
Seq A exon
AGCCGGCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGATCTGTGGTCTCTGGAGCTGTGGTTGCTGCTGTGATATGGAGGAAGAAGAGCTCAG
Seq C2 exon
GTGGAAAAGGAGGGAGCTACTCTAAGGCTGAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204592_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.387 A=0.000 C2=0.667
Domain overlap (PFAM):
C1:
PF0765410=C1-set=WD(100=92.5)
A:
PF066236=MHC_I_C=PU(8.0=5.0)
C2:
PF066236=MHC_I_C=FE(44.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCATGAGGCCACCCTGAG
R:
AGTAGCTCCCTCCTTTTCCAC
Band lengths:
258-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains