HsaEX6047983 @ hg19
Exon Skipping
Gene
ENSG00000188107 | EYS
Description
eyes shut homolog (Drosophila) [Source:HGNC Symbol;Acc:21555]
Coordinates
chr6:64708968-64791895:-
Coord C1 exon
chr6:64791749-64791895
Coord A exon
chr6:64776231-64776384
Coord C2 exon
chr6:64708968-64709076
Length
154 bp
Sequences
Splice sites
3' ss Seq
ATATTCTTTTTTTCTTAAAGGTA
3' ss Score
10.09
5' ss Seq
ACGGTAAGT
5' ss Score
11.81
Exon sequences
Seq C1 exon
ATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCCTTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTTTACA
Seq A exon
GTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCTCAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACG
Seq C2 exon
CTACACAACGCCTGTTGGCAGCCCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188107-'43-43,'43-40,44-43=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.111
Domain overlap (PFAM):
C1:
PF0221019=Laminin_G_2=PU(8.6=24.0)
A:
PF0221019=Laminin_G_2=FE(36.7=100)
C2:
PF0221019=Laminin_G_2=PU(42.9=81.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCAGGTTTATTCTTTCCATCTTTCA
R:
AGGCATGGGAAATCTCTGTGT
Band lengths:
250-404
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)