HsaEX6065029 @ hg19
Exon Skipping
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:23336]
Coordinates
chr12:9013520-9016604:+
Coord C1 exon
chr12:9013520-9013551
Coord A exon
chr12:9013731-9013893
Coord C2 exon
chr12:9016390-9016604
Length
163 bp
Sequences
Splice sites
3' ss Seq
TCTTCATCTTCACTTTTTAGGAC
3' ss Score
11.4
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
CTGCATTGCTGGAGATGGGAAAGGATGTAGAT
Seq A exon
GACCCAATGGTGAGTCAGGGTCTACGGTGTCTCAAGAATTCGGCCACCTCCACGACCAACCTCTACACACAGGCCCTGTTGGCTTACATTTTCTCCCTGGCTGGGGAAATGGACATCAGAAACATTCTCCTTAAACAGTTAGATCAACAGGCTATCATCTCAG
Seq C2 exon
GAGAATCCATTTACTGGAGCCAGAAACCTACTCCATCATCGAACGCCAGCCCTTGGTCTGAGCCTGCGGCTGTAGATGTGGAACTCACAGCATATGCATTGTTGGCCCAGCTTACCAAGCCCAGCCTGACTCAAAAGGAGATAGCGAAGGCCACTAGCATAGTGGCTTGGTTGGCCAAGCAACACAATGCATATGGGGGCTTCTCTTCTACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535-'27-29,'27-27,28-29=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.083
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(9.8=100)
A:
PF076789=A2M_comp=FE(22.0=100)
C2:
PF076789=A2M_comp=FE(28.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCATTGCTGGAGATGGGAA
R:
TGAGTAGAAGAGAAGCCCCCA
Band lengths:
246-409
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)