HsaEX6065029 @ hg38
Exon Skipping
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr12:8860881-8864008:+
Coord C1 exon
chr12:8860881-8860955
Coord A exon
chr12:8861135-8861297
Coord C2 exon
chr12:8863794-8864008
Length
163 bp
Sequences
Splice sites
3' ss Seq
TCTTCATCTTCACTTTTTAGGAC
3' ss Score
11.4
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
GGTGGTGTTGATGATGAGGTCTCCTTGACTGCGTATGTCACAGCTGCATTGCTGGAGATGGGAAAGGATGTAGAT
Seq A exon
GACCCAATGGTGAGTCAGGGTCTACGGTGTCTCAAGAATTCGGCCACCTCCACGACCAACCTCTACACACAGGCCCTGTTGGCTTACATTTTCTCCCTGGCTGGGGAAATGGACATCAGAAACATTCTCCTTAAACAGTTAGATCAACAGGCTATCATCTCAG
Seq C2 exon
GAGAATCCATTTACTGGAGCCAGAAACCTACTCCATCATCGAACGCCAGCCCTTGGTCTGAGCCTGCGGCTGTAGATGTGGAACTCACAGCATATGCATTGTTGGCCCAGCTTACCAAGCCCAGCCTGACTCAAAAGGAGATAGCGAAGGCCACTAGCATAGTGGCTTGGTTGGCCAAGCAACACAATGCATATGGGGGCTTCTCTTCTACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535-'43-47,'43-42,44-47=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.083
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(9.8=100)
A:
PF076789=A2M_comp=FE(22.0=100)
C2:
PF076789=A2M_comp=FE(28.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGAGGTCTCCTTGACTGCGT
R:
CATTGTGTTGCTTGGCCAACC
Band lengths:
251-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains