HsaEX6065068 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9098607-9101207:-
Coord C1 exon
chr12:9101144-9101207
Coord A exon
chr12:9099381-9099523
Coord C2 exon
chr12:9098607-9098756
Length
143 bp
Sequences
Splice sites
3' ss Seq
TCATTCTCTTTGTGCCCCAGTGA
3' ss Score
7.8
5' ss Seq
AAGGTGTGT
5' ss Score
6.64
Exon sequences
Seq C1 exon
ATAATGGCAAAGGGAGGCATTGTCCGAACTGGGACTCATGGACTGCTTGTGAAGCAGGAAGACA
Seq A exon
TGAAGGGCCATTTTTCCATCTCAATCCCTGTGAAGTCAGACATTGCTCCTGTCGCTCGGTTGCTCATCTATGCTGTTTTACCTACCGGGGACGTGATTGGGGATTCTGCAAAATATGATGTTGAAAATTGTCTGGCCAACAAG
Seq C2 exon
GTGGATTTGAGCTTCAGCCCATCACAAAGTCTCCCAGCCTCACACGCCCACCTGCGAGTCACAGCGGCTCCTCAGTCCGTCTGCGCCCTCCGTGCTGTGGACCAAAGCGTGCTGCTCATGAAGCCTGATGCTGAGCTCTCGGCGTCCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899_MULTIEX1-2/17=1-3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.020
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=FE(14.1=100)
A:
PF077039=A2M_N_2=FE(27.5=100)
C2:
PF077039=A2M_N_2=PD(26.2=78.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCAAAGGGAGGCATTGTC
R:
CGAGGACGCCGAGAGCTC
Band lengths:
210-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains