HsaEX6065074 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9080094-9090023:-
Coord C1 exon
chr12:9089902-9090023
Coord A exon
chr12:9089200-9089251
Coord C2 exon
chr12:9080094-9080177
Length
52 bp
Sequences
Splice sites
3' ss Seq
TTTCTTTCTTTTACCTAAAGCCT
3' ss Score
6.44
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GAAATGTGAATTTCACTGTGAGCGCAGAGGCACTAGAGTCTCAAGAGCTGTGTGGGACTGAGGTGCCTTCAGTTCCTGAACACGGAAGGAAAGACACAGTCATCAAGCCTCTGTTGGTTGAA
Seq A exon
CCTGAAGGACTAGAGAAGGAAACAACATTCAACTCCCTACTTTGTCCATCAG
Seq C2 exon
GTGGTGAGGTTTCTGAAGAATTATCCCTGAAACTGCCACCAAATGTGGTAGAAGAATCTGCCCGAGCTTCTGTCTCAGTTTTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899_MULTIEX1-10/17=9-11
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.146 A=0.056 C2=0.069
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGGTGCCTTCAGTTCCTGA
R:
GACAGAAGCTCGGGCAGATTC
Band lengths:
138-190
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains