HsaEX7007562 @ hg38
Exon Skipping
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123931941-123933511:+
Coord C1 exon
chr12:123931941-123932108
Coord A exon
chr12:123932618-123932731
Coord C2 exon
chr12:123933331-123933511
Length
114 bp
Sequences
Splice sites
3' ss Seq
TGCATTTTAAATTTTGATAGCTC
3' ss Score
5.23
5' ss Seq
TAGGTGAAA
5' ss Score
1.84
Exon sequences
Seq C1 exon
GCCTTGGCTGGAGAAGTTGGAATGAGCAATGAGTTAGATGATGTGGCCAGGTCTCTTTTTATCGGGCATATCCCTAATATCTGGAGAAGGCTTGCTCCTGACACCTTAAAGTCCCTTGGAAACTGGATGGTCTACTTCCTGCGGCGGTTCAGCCAGTACATGTTGTGG
Seq A exon
CTCTTGTTGGATGGTTCTTAGAAAGGCTGAAACCACAGTCTATGAGAGTGCTTCTTTCCTCACTCCGCTGCAATGCTGCGTTCTTAACATTTTGGATCACTGTCTCCCTGATAG
Seq C2 exon
GTGACCGAGAGCGAGCCCAGCGTGATGTGGCTCTCGGGGCTGCACATCCCTGAGTCCTACCTCACGGCGCTGGTGCAGGCCACCTGCCGGAAGAACGGCTGGCCACTGGACCGCTCCACCTTGTTCACACAAGTGACCAAGTTCCAGGATGCAGATGAAGTGAATGAGCGGGCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653-'103-102,'103-101,105-102=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(69.6=100),PF154071=Spo7_2_N=WD(100=78.6)
A:
PF0302810=Dynein_heavy=PD(3.8=42.9)
C2:
PF0302810=Dynein_heavy=FE(8.4=100)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAAGGCTTGCTCCTGACAC
R:
GCCCGCTCATTCACTTCATCT
Band lengths:
258-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains