HsaINT0049286 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123931941-123933511:+
Coord C1 exon
chr12:123931941-123932108
Coord A exon
chr12:123932109-123933330
Coord C2 exon
chr12:123933331-123933511
Length
1222 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
3' ss Seq
TTGTCCTCTCTTCTCTCCAGGTG
3' ss Score
12.83
Exon sequences
Seq C1 exon
GCCTTGGCTGGAGAAGTTGGAATGAGCAATGAGTTAGATGATGTGGCCAGGTCTCTTTTTATCGGGCATATCCCTAATATCTGGAGAAGGCTTGCTCCTGACACCTTAAAGTCCCTTGGAAACTGGATGGTCTACTTCCTGCGGCGGTTCAGCCAGTACATGTTGTGG
Seq A exon
GTAAGTGGCACGTCACCGCCTCCTCTCTGCCGATTCAGGTGTCAGCCTAGACTCCTCAAACCACCTCCCAATCCCCTCTTTCCATTGCCCAGCAGTAACCTCTGTTAAAGTTTATTGGGTGCTCTGGAAATGGTCTGAGATTCTTACAAGCCTATCTGTATCTTTTGTTTTTCCTTTTCTTTTGAAGACTTTGAAGCATACTCTTACATACCCGATTATTTTATCTAAGTGTATATCTTGGCACTTGTTCCATATTAGTACACAGCTAGCTCGTTCTTTTTTAGAGTATGCCATTGTACAAATGTTTCATATCCTTTCTCCTCCTTCTGTATCCTAAAAATATGGTAACTGCCTACATTTCGGTGGTTACCATTTTTTTTTTTTTTTTGCTAATACAAATAACATTCTGGTGCACATGTATATGAATATGCATAGGGGTATATTCCATGGGTAAATTCTGACAGTGGAAGAGTTGGATCAAAGAGCTTGTGCATTTTAAATTTTGATAGCTCTTGTTGGATGGTTCTTAGAAAGGCTGAAACCACAGTCTATGAGAGTGCTTCTTTCCTCACTCCGCTGCAATGCTGCGTTCTTAACATTTTGGATCACTGTCTCCCTGATAGGTGAAAATAATATCTCATTGTTTTGCATGTCTTTAATTATGGTGAGTCTGAGCGTATTTTGCATGCTTTACAGACATTTTGTGTTTGTTTTTCTGTGAATTGTCCTTTTGTATCTGGATTTCATTTTTAGTGAGGTCTCCATCTTTCTCATTGATGTTTAAGAGCTCTTTGCAAATCAAAGAAATTAGCCCTTGGTCTGCCAGTGTTGCAGGTATTTCTCCAAGCTTGTCATAAGTCTTGACTTTGCTTACGGTATTTTTTCCACAGAAAAGCTTTACATTTTTCCGTAGTCAAACCTACAAGGCTTTTCTTTTTTATCCTGGGCTTTGTATTTCCTACTCCACGATATGAAAGCATTCATTGGAGATGTGGCCCAGTACTTTTGTGGTTTTATTTATTTTTATATCTAAATCTTTGATCTACCTGGAATGTGGCAGTCCAGATTGTTTTTCTCAGACAGGCGGCCAGTTGTGCCAACGCCATCTTTTGCCACTTAGGTGAAATATGTCTTTTATCATAAACTAAACTTCCAGGCCAGCTTTGACCTGGCATTGGATGGCAGCCCCAGGCTCCCAGCACTTGTCCTCTCTTCTCTCCAG
Seq C2 exon
GTGACCGAGAGCGAGCCCAGCGTGATGTGGCTCTCGGGGCTGCACATCCCTGAGTCCTACCTCACGGCGCTGGTGCAGGCCACCTGCCGGAAGAACGGCTGGCCACTGGACCGCTCCACCTTGTTCACACAAGTGACCAAGTTCCAGGATGCAGATGAAGTGAATGAGCGGGCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:75
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(69.6=100),PF154071=Spo7_2_N=WD(100=78.6)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(8.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTTGGCTGGAGAAGTTGG
R:
CGCCCGCTCATTCACTTCATC
Band lengths:
342-1564
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development