HsaINT0000050 @ hg38
Intron Retention
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9068740-9069813:-
Coord C1 exon
chr12:9069745-9069813
Coord A exon
chr12:9068843-9069744
Coord C2 exon
chr12:9068740-9068842
Length
902 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
AATTGACTTTTGCTTTCCAGGTG
3' ss Score
9.9
Exon sequences
Seq C1 exon
CTTGAAAGATCTAACCATGTGAGCCGGACAGAAGTCAGCAGCAACCATGTCTTGATTTACCTTGATAAG
Seq A exon
GTAAGAGAACTTCCAGTCTATTTGCAAAAAAACGTAGATAATAATCCTCTAAGGGAACATCTGGGAAGGTAAATGCATTTTAGAAACATCACTTCCATGCTAGAAATTTGAGAATTCTAATGTTAACTCTAAAAGAATGTTCTTCTCTCCTTTATTTATATTTCACCAGGGATTACAGGTAGAAATGGCTTATTATGATCTTGGGATATGAATATTCCTAAAATCCCATAAGCAAGAAATCTTCACAAAATGTGTTTATTATGTTGACAAGTTTTTTGGATACCCAGTAATATAAGGAAGTAGCCCTTGTGATTAGTCAATTATTAGTTAATTATCAACATACTCAACAACAATATGAAAGGGAAAAAAAACTGTCAGTCTCCACAAGGACTTGAACCATAAAATAATAAGACCAGTTCACCAGTAAACCAATCTGATTTTATAGATATGTGTGGTAGGAGAGTTTGTTCATGCATAAGTTGATGGGAATTATAGTTTACAAATTTTATGAAACTTAAGCCTGGGAAGATCAACCTTTTAGATGCCTCTTTGAGTCTACGCAAGTATTCCTGCAAGACAGAGAAGTCAAACTATACCAAATCTCTGGATATTAAAAAATGAACACAGTTAGTCATCCAATAAAAAGTATATATCATTTACCCCCATGAACAGAGCTATGTATTGGCATTGACAGAGGTATATGCGTTATGTTAGTTATTTAAGAAATAATCTGGAGAATTTATCATCCCCTCTGAGAGATTTCTGCACAATTTAATTAAGGACCCTATAGTGTGCTGTAGGATAATAAAGCTTTTCCCCCAAAAAACAGGTGAATACTTAAACTAATTCAAAGAGAGAAGAAAGCTTCCTGAAAGGTCATTTAATTGACTTTTGCTTTCCAG
Seq C2 exon
GTGTCAAATCAGACACTGAGCTTGTTCTTCACGGTTCTGCAAGATGTCCCAGTAAGAGATCTGAAACCAGCCATAGTGAAAGTCTATGATTACTACGAGACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899:ENST00000318602:33
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.087 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF076779=A2M_recep=FE(25.0=100)
A:
NA
C2:
PF076779=A2M_recep=FE(38.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development