HsaINT0000069 @ hg19
Intron Retention
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:23336]
Coordinates
chr12:8975778-8976478:+
Coord C1 exon
chr12:8975778-8975961
Coord A exon
chr12:8975962-8976315
Coord C2 exon
chr12:8976316-8976478
Length
354 bp
Sequences
Splice sites
5' ss Seq
CTTGTAAGC
5' ss Score
4.33
3' ss Seq
AAGTCCCCTTTCTTGGTCAGGTA
3' ss Score
5.73
Exon sequences
Seq C1 exon
AAACTACCTGGTGACATTACCAGCCCGGCTAAATTTCCCCTCCGTTCAGAAGGTTTGTTTGGACCTGAGCCCTGGGTACAGTGATGTTAAATTCACGGTTACTCTGGAGACCAAGGACAAGACCCAGAAGTTGCTAGAATACTCTGGACTGAAGAAGAGGCACTTACATTGTATCTCCTTTCTT
Seq A exon
GTAAGCACAGACTCAGCCCTCACTCGAATCCCTTACTTGCCTATTCTCCTCCCTAGGCTCACTATAATCTACTTTAAGTATAATTTCTGTTATCTTTTGCCACGGCCTCTAAACCTATTTTTTCTCAACTTAACCTCAATCCCCGGCTATAACTCACCCACGGTTTCCTCGACCTAGGATTTCTCCCTTTAGTTCCTGACCTTAATTCTTCCTCGTGGTAATTTGTTTTATGTCTCTATCCTTGCTACCCCCATCTAACTCAGCTCTTTCCTTTAACTCACTGTTGGGTTGAGACCAGTTGATTCTGTTCCCCCAATCCCTTACCCCTCCCCAGAAGTCCCCTTTCTTGGTCAG
Seq C2 exon
GTACCACCTCCTGCTGGTGGCACAGAAGAAGTGGCCACAATCCGGGTGTCGGGAGTTGGAAATAACATCAGCTTTGAGGAGAAGAAAAAGGTTCTAATTCAGAGGCAGGGGAACGGCACCTTTGTACAGACTGACAAACCTCTCTACACCCCAGGGCAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535-A2ML1:NM_144670:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.036
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0183514=A2M_N=PU(13.6=29.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACATTACCAGCCCGGCTAA
R:
CTTGCTGCCCTGGGGTGTAG
Band lengths:
336-690
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)