HsaINT0000391 @ hg19
Intron Retention
Gene
ENSG00000165029 | ABCA1
Description
ATP-binding cassette, sub-family A (ABC1), member 1 [Source:HGNC Symbol;Acc:29]
Coordinates
chr9:107562100-107562865:-
Coord C1 exon
chr9:107562791-107562865
Coord A exon
chr9:107562270-107562790
Coord C2 exon
chr9:107562100-107562269
Length
521 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
3' ss Seq
CCTGGTATGTTTTCTTTCAGGTG
3' ss Score
11.06
Exon sequences
Seq C1 exon
GACAGTTCTGCAGATCGATTTCTCAACAGCTTGGGAAGATTTATGACAGGACTGGACACCAAAAATAATGTCAAG
Seq A exon
GTAAACCGCTGTCTTTGTTCTAGTAGCTTTTTGATGAACAATAATCCTTATGTTTCCTGGAGTACTTTCAACTCATGGTAAAGTTGGCAGGGGCATTCACAACAGAAAAGAGCAAACTATTAACTTTACCAGTGAGGCAGTACGGTGTAGTGTAGTGATTCAGAGAATTTGCTTTGCCACCAGACATACCAGGTAACCTTGACTAAGTTACTTAACCTATCTAAACCTCAGTTCCCTCATCTGTGAAATGGAGACAGTAATCATAGCTATTTCCAAACTGTTGTGAGAATTCAATGAGTTAAAGGTATAAGGTCCTCACCACAGCGCCTGCCCACATAGTCAGTGATCACTATGTCCTGAACACTGTAATTACTTCGCCATATTCTCTGATCATAGTGTTTTGCCTTGGTATGTGACTAGAATTTCTTTCTGAGGTTTATGGGCATGGTTGGTGGGTATGCACCTGCCTGCAGGAGCCCGGTTTGGGGGCATTACCTTGTACCTGGTATGTTTTCTTTCAG
Seq C2 exon
GTGTGGTTCAATAACAAGGGCTGGCATGCAATCAGCTCTTTCCTGAATGTCATCAACAATGCCATTCTCCGGGCCAACCTGCAAAAGGGAGAGAACCCTAGCCATTATGGAATTACTGCTTTCAATCATCCCCTGAATCTCACCAAGCAGCAGCTCTCAGAGGTGGCTCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165029-ABCA1:NM_005502:35
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(4.6=100),PF126932=GspL_C=FE(43.6=100)
A:
NA
C2:
PF126982=ABC2_membrane_3=FE(10.6=100),PF126932=GspL_C=PD(1.8=1.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAGATCGATTTCTCAACAGC
R:
AGAGCCACCTCTGAGAGCTG
Band lengths:
238-759
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)