HsaINT0003964 @ hg19
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136314904-136319741:+
Coord C1 exon
chr9:136314904-136315086
Coord A exon
chr9:136315087-136319536
Coord C2 exon
chr9:136319537-136319741
Length
4450 bp
Sequences
Splice sites
5' ss Seq
TAGGTGAGT
5' ss Score
8.83
3' ss Seq
GGGGTCTTCTCTTCCTGCAGGTG
3' ss Score
11.21
Exon sequences
Seq C1 exon
GTGGCAGTACAAGCTGGCGGCCTGCAGCGTGAGCTGTGGGAGAGGGGTCGTGCGGAGGATCCTGTATTGTGCCCGGGCCCATGGGGAGGACGATGGTGAGGAGATCCTGTTGGACACCCAGTGCCAGGGGCTGCCTCGCCCGGAACCCCAGGAGGCCTGCAGCCTGGAGCCCTGCCCACCTAG
Seq A exon
GTGAGTCAGCCGGTGATGGGAGGGGCAGCTCCTGGTGTGTGCAGATGCCAGGCCAGGCGCTGTGGTGTGTGCCTGTAATCGCAGCTACTTGGAAAGCTGAATCAGGAGAACCACTTGAGTCCAGGAGTGCAAGTCCAACCTGGGCAACACAGTGAGACCTCATCTCTAAAAAAAAAACAAGACGGGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCGCTATGGAAGGCTGAAGCGGGTGGATTACCTGAGGTCAGGAGCTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTTTACTAAAAATACAACAATTAGGCTGGGCGCGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGTCCAACATACAGAAACCCTGTCTCTACTAAAAATACAAAATTAGCCGGGTGTGGTGGTACATGCCTGTAATCCCAGTTACTTGGGAGGCTGAGGCAGAATCGCTTGAACCGGGGAGGCCAAGGTTGTGGTGAGCCAAGATTACGCCACTGGACTCCAGCCTGGCTAACAGCAGCAAAACTCCATCTCAAAAAAAAAAAAAAAAAAAGAAAACCCACAAAAATTAGCCTGGCGTGGTGGTGTGCACCTGTCATCCCAGCTACTTCAGAGGCGGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATGGCGCCGCTGGCACTCCAGCCTGGGCTACAGAGCGAGACTCCGTCTCAAAAACAAAACAACAAAACAAAACAAGACGGGGTGGGGGGCTCAGTGGCCCAAGAGCCAGTCTGTAAGGAATAGGGCTACCTGGCAGGCTGTGCTAGTTGTGGGAGGTGAAGTTTAAGCACCATGCAGGCAGGGTGCAGTGTGGGGAGGCCTGGGGGACAGAGGAGGCAGCATTTGAGCAGAACCTAAAGCTGTGAGCACCAGCATTCTGATGTGGAAGACGGGAGGGATGGAGGTCTCCACAGGGACACACACAGCCACACTAGGACACGGGACAGAATCATGTTCAAGTCCGTGGGGTCCGGAGCCCAGTGGTAAAGGGCGAACATTTGCCTACCTCATTTACAATTCTTTAATGGTTTCTTTTTGTAGGTTTGCATTTTTAGTAAAGAAATACTTTTCTATATCATACAGAAACGTCCAGAAAAGAATGTAACAGACATGTATGTTCCAGCACTCCAGTTTAATAGATAGCATCCTACTGCCATGTTTCCTTCCTGTCCACTTACTTTTATTTATTTAATTTATTTATTTTGAGACGGAGTCTCGCTTTGTTGCCCAGGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCCATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGAATACAGGCACCCACAACCACACCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATATTGGTCAGGCCGATCTTGAACTCCTGACCTCAGGAGATCTGCCTACCTCAGCATTCCAAAGTGCTGGGATTACAGATGTGAGCCATCACACCTGGCCAGCCTCCTTAGTTTTAAATAAATCCAGTTACAGATAAGATTTCACTTAAATTTAGGCTGGTCATGGCTCACGCCTGTAATCTCAGCACTTCAGGAGGCTGAGATGGGTGGATCATTTGAGCCCAGGAGTTTGAGACCAGCCTGGACAACATGCCAAAACCTTGTCTCTACTATAAATACAAAAATTAGCCGGGCATGGTGGTGCATGCCAGTATCCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACCTGAACCTTGGGAGGTCAAGGCTGCAGTGAGCAGAGATCACACCACCACTGCATGCCAGCCTGGGCAACAGCATGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGATTTTACTTAAATTTAAACCCTGTACTAATCTGTGATTTATTTGGAGTATGTTGCAAAGTAGGGACCAAAGGATTTTTTTTTTTTTCTAAATTGTTAACTAGCATCTGTTGGACAAGCCCTGATGCCTCCAGGTGGCTCCTTGGTGGTATTGGTGTGTGTTAGAATCTATGTCTGGGCTTTCTACTGGGTTTTTTTCTTCTCCTTTTTTTTTTTTGAGACAGTTTTTCTCTGTCACCCAGGGTGGGGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTTTCATGCCTCAGCTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACCACCCCCAACTGATTTTGTGTTTTTAATAGAGACAGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCAGGTTCTGTTTTTTGTGCTTTTTTTTTCTAGCTATTCTCTTGCCCATACAAAATTGTTTTAAATGTTGTAGCTTTATAACCATTTAACATCTGTGTCACTAGTGTGTCCTGATTTCTTTGCCTATGCTAAAGTCCCTTGGCTGTGTGTCCCATTTATTTTTCCACATCACATTTAGAGATGATCTGGGATTTTATGGGAATTGCAGGGTTTTTCACACTGCACGCTGCCTGCATGGTGCTTAAACTTCACCTCCCACACCTAGCACAGCCTACCAGGTAGCCCTGTTCTCTACAGACCACCTCTTGGGCCACTGAGCCTCCCCTCACTTTTTTTTAGAGATGGGGTCTCACTATGTTGCCCAGTCTGGACTTGAATTCCTGGGCTCAAGTGATCCTCCTGCTTCAGCCTCCCGAGTAGCTGGGATGCAGGCACACACTACATGAGCTCTGGCCATCCCTCTGACGTTGCTGTAGCCACGCTGGCCTCATTGTCCTGGAACATTCCAGGGATACTCCCCTGACTTAGGGCTTCTGTGCTAGCTCTCGCTGCCTGATGTCTTCTGTGGATATCCTCGAGGCCCTGGATATCCCTCCCCCAGGCTCGGCTCAGACACCACAACTCCAAAGTGGCCCAGTGCCCTCCCTGAGCGTCGGTCCAGAACGGCACTCTCGTCCCTCCTGTGACGCTCTGCTTGGCACTTTGGGAGGCTGAGGCGGGAGGATTGCTTGAGCCCAGGAGTTCTAGACCAGCCTGGGCAACATAGTGAGACCCCGTCTCTACAAAAAATACAAAAATTGGCTGTGCGCGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCGAAGGCGGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCTGGGTGTAGTGGTGGGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGACGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATTGTGCTACTGCACTCCAGCCTGGGTGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCGATGAGTGAGACTCCATCTCAAAAACAAAAACAAACAAACAAAAATTACAAAAATTAGCCAGGCATGATGGCACATGCCTGTAGTCTCAGCTACTTGGGAGGCTGAGGTGAGAGGATGGCTTGAACCCTGGAGGTTGAGGCTGCAGTGAGCCGTGATCACACCACTGCCCTCCAGCCTGGGTGACAGGGCGAGACCGTGTCTCAAAGAAAACCATTAAAATAAAATAAAAAATAAAATTTCTGCGATGCACACGACAGCCTCCACAGCAAATCAGCATCCAGTTGCTCATGCCAGTGATGCCCCAATGGAGAACAATCCACGCTCTGAGAGGAGGTGGGGTCTGGTTTGGTTCACTGCCACCTCCCAGTGTCATGTAGAACAGTGCCAAGCCGCGGAAGGCACGGGTCCAAGAGGCAGCGCTGCAGGGTCATGGGGGAGCACAGTATTGCGATGAAGATCCCAGCTCCCTTGCAGGCTGCCTGGGTTTGTGTCTGGGCTCTGAAGAATGCGGGCCATAATTAGTTATTGATTGATTACAGATCAACATGGGCAGCCTTCCCTTGCCCAAGGGAAGGGAACTCGGCCTTCCCTTGCAGAACGTGGGGTGTTGAGATCTGTCTCCTGTTACCCAGGGGCTCGCTTCCTGTTGCTGTTACTTGGGTCCATAGGCAACCCCTGGGGTGCTGACAGGTGTTCTGTGATAAAGGCGACTAGAGGGGGATGTGCAATTAGGGAAACAGGGGCCTCTTCCCCCTAGGGCCTTTTGGTAGCTCTCCTGTGGCCGTGAGCCCTGGCCCCAGACAGGAGGGGCTCAGTGGCTGCACTTTCCATCTTGCCTGGCCACGGAAGCTGTCTAGGCAACTGTCCGAGTACACGTGGGTGGAGAGGGGCCTGCGTGGGGCAGTACTGTCTCTGGGGAGACCTAGCCTCTCTCTGGGGTCTTCTCTTCCTGCAG
Seq C2 exon
GTGGAAAGTCATGTCCCTTGGCCCATGTTCGGCCAGCTGTGGCCTTGGCACTGCTAGACGCTCGGTGGCCTGTGTGCAGCTCGACCAAGGCCAGGACGTGGAGGTGGACGAGGCGGCCTGTGCGGCGCTGGTGCGGCCCGAGGCCAGTGTCCCCTGTCTCATTGCCGACTGCACCTACCGCTGGCATGTTGGCACCTGGATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-ADAMTS13:NR_024514:13
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=WD(100=90.3)
A:
NA
C2:
PF0009014=TSP_1=WD(100=59.4),PF0009014=TSP_1=PU(12.2=8.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)