HsaINT0004316 @ hg19
Intron Retention
Gene
ENSG00000197859 | ADAMTSL2
Description
ADAMTS-like 2 [Source:HGNC Symbol;Acc:14631]
Coordinates
chr9:136409592-136412335:+
Coord C1 exon
chr9:136409592-136409672
Coord A exon
chr9:136409673-136412159
Coord C2 exon
chr9:136412160-136412335
Length
2487 bp
Sequences
Splice sites
5' ss Seq
TAGGTGGGT
5' ss Score
5.56
3' ss Seq
CGGCGGCTTTGCCCTTCCAGCTC
3' ss Score
9.36
Exon sequences
Seq C1 exon
GTTACTCTCTGGTGACCCACATCCCGGCTGGTGCCCGAGACATCCAGATTGTAGAGAGGAAGAAGTCCGCTGACGTGCTAG
Seq A exon
GTGGGTACGCAGTGTCTGGCAGCTGCCTCACTGAGCTTTTGGTTGTGGAGCGTTGTGCGTGGCAGAGAAGGGGCACTTGACCCTGGACCCCTTCCTCCAGGACAGGGATGGACCAGTGCTGTGGGCATGGCTGCAGGAGCCAGAACTTGAGCCAGCTGTGTGGGTGTGGCTGGGGTGCTCACAGGGGAGCCAGCTTTACCCCTGTGCATGGCAGGACCTTGAACTCAGAGCTGCTGGACAATGGGAGGGTGGTGATGTTGGGTGGTGAGCTCCCTGTCACTCGAGAGCCTGGCACAGGCAGAAGCTGGGGGCCGCTGCAGATGAGATCCCTGTGGGGTTCGAGGAGTGAGTCTCAGGAGATGACAAGGTCAAGGTAGCACTGAGAGGAAGTCGGTGCAGAGGTAGGATTCCGACTCAGGTCTGGGGTCTCATGCTGATGTTCTTGCCATTAGTCAGACTCCGCTGGGAGGCTGGGCTGTAGGAGGGGAGTCCTCTAACCTGAGTATTCTGGAGTTGTTTCCATGATGGACAGAGTGGTGAGGCCCCATCTTGGTGGCAGATTTTGAGTGTAGGGAGCCTTGGTGGCAAATTTTGGAAGAGCCCTCTGGGAAGATGGAGTATTGGCCGAGCAGCGTGCCATGTCTGCACCCCTTGGGCCACAGTGGGCAGGTGCTGACACCTGTGAGCTGCTCTGTGCTCGGCCCTTCCCTTTATGGGGCGGGCTTGGGTATAGGGACGCTGTTCTTGGACACAGGTGCAGCCCCAAACCTGACACTACCTGGGTTTACTCCCCCCACTGCCTCCCACTCTTCTTGAGAGCCAGAACTGGTGGGGTGAAGCCCATCTCCTAAGGGGGTGCTGGAAGAGGAGGCTTTGCTGAAGGTCTTCAGGCTGGGACCCACCTTGGGTTCTCCTGTTCCCTCTCCAGAGCCTAAGGGCCAGCCCTCCGTATGTGCCCTGGGGTCTGAGTGCCCCTGCCCCAGCAGGTCTGTGCTGCAGATGCTGGCTCCACCACCCAGCGCCCTGGGGGCTACTCCCTGGCCCGAGCGGGGAGCCGGGCCTCTCGCCAGGCCAGTTGCTTTGTCGCTTGCTTGCTGGGAGAGTGGAGAGGCCAGGAAACTCCACATTCTCTGAGCTGGCTGCAAAGCTCTTGCTCTTGAAACAGACGCGTAGAAATACCAAGGGTGGGCTCGGAGCACTGGGAAAGCCGCAGGAAGGAAGGTCATTACTGTCAGGAAACAGGTTTTGGACGAGAGCCTCGGATTTAACCCTGTGCATATACCTGGAAACAGGGCCGAGACAACCAGGCCCCAGCACACTCCCCCTCGCAGAACTTGGACTCTAATTTGCGTTATCTTCTGACTTTTCTACGTGAAGGGGGTTTTTCAAGCAGACATGTCCTGCTTGTTGCGTCTGTCTGATAATAAATTAATTGCCCCGGCTCCTCTGTTCATATTGCATCAGGAATTTGGAAGCCGAACTCCTCTTCTCCCACTGGCCAGTTCCTGGAACTGGCTTTAAGGACACCCTTTGGAAGACAGAGTGTCCCGAGCGCCGAATCGGCCTCCTCCCTGCGTCCCCAGCCCTGGAGGCCCCCCACCTCTTCTCACTCTCCATGGCCCCAGGGAGGATCAGTTCCCCTTGAAACCCCACCAGCTCTGGGCTGTTGTTCCAGTCTGCAGGGGTGGTGGGGAGTGGGGGCTGCAGGGCTTCATGGGCCATTTGTTTCCATCCTGAGCTTCCATCAGGCTGGAGTTAGGCCCTGGGAGTGCCCACCCACCCGGCCCCAGGAAGAGGGCAACTGAGATTGCACCAGGCCACCCTGGCCTGATTGGGCACCCAGGAAGAGGGTGACTGAGATTGGACCAGGCCGCCCTGGCCTGATTGAGCACCTCGGCCAGGCCTGGGTGCACGGGTTGACTGGGTGAAGGGTCAGCATGGCCCTGCCTGCAAGGGCAGCAGGAAGTCTCTGCTCCCGTGGAGAGGTTGGAGCTGGCCAGCTCAGGGCGATCCCCAGGAAAGGCCTGGTGGTCAGCACACCCATGCCAGCCAGGCCAGGGCTGCAGGGTCACTCTGTGTGGATGACGGGAGGGGCACCCAGGACCCCTGCTGCCTCGTGTGTGCCTTCCACAGGCCACAGACTCTCCTGCTCCAGACTGGGTCCCTTGGTTGTGGTGCGACCTCATTACCTTGCAGCCCCTCAGCTTCTTCACAGGTAGCCACAAGAACAGGACCAAATGGGTCCCCAGCCAGCCGTGTTCAATGTCTAGACCAGTCCTTCATTGCTGATTTTAGGCTGAGAGGAACGTGCGTTTGCCCCTCCTCCGCATTCACTGGCCAGACTCTCCATGATGGGAGTTTCCTGTCTCGGGAGCATTTGAGCCGGGGTTCTGGAGGGCAGGGCTGGTGGTGGTTCCCTGAGTTGGTGACACTGGCTCCTCCCCCAGCCAGTTTGGCCTTTTGTGACCGGCGGCTTTGCCCTTCCAG
Seq C2 exon
CTCTTGCAGACGAAGCTGGCTACTACTTCTTCAACGGCAACTACAAGGTGGACAGCCCCAAGAACTTCAACATCGCAGGCACGGTGGTCAAGTACAGGCGGCCCATGGATGTCTATGAGACCGGAATCGAGTACATCGTGGCACAGGGGCCCACCAACCAGGGCCTGAATGTCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197859-ADAMTSL2:NM_001145320:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.034
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=FE(22.9=100)
A:
NA
C2:
PF059869=ADAM_spacer1=FE(49.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)