HsaINT0017369 @ hg38
Intron Retention
Gene
ENSG00000186716 | BCR
Description
BCR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:1014]
Coordinates
chr22:23268408-23271592:+
Coord C1 exon
chr22:23268408-23268515
Coord A exon
chr22:23268516-23271531
Coord C2 exon
chr22:23271532-23271592
Length
3016 bp
Sequences
Splice sites
5' ss Seq
GAGGTAATG
5' ss Score
8.73
3' ss Seq
ATGCGCTTTTCTCTCTGCAGAAC
3' ss Score
11.93
Exon sequences
Seq C1 exon
GCCAGCCAGCTGGGTGTGTACCGGGCCTTCGTGGACAACTACGGAGTTGCCATGGAAATGGCTGAGAAGTGCTGTCAGGCCAATGCTCAGTTTGCAGAAATCTCCGAG
Seq A exon
GTAATGCCTTGATGCCGTTCAGACAGGTGCACCGCTGACTCCCACCTGTACCCTCCACCTCCCGAGGAGAACAGAGTGCACCAGATCAAGATCTGGTCGTGAACCCCAGCTGTTTCCAGATTCTGTTGGGTTCGTTGCGTCAGCCCTGTGCTGGGGATGCTGTTGTGCGCAGACCGAAGGAGCAGCCCACAGGGCGTCCTGCCTCCCCGGGGGCGAGGGCCTGATTCTGGGGGTTGCCGAGTTCCGGGGACACTCTTTGCACTGTCTGTCTGCAGTGAGGGGTGTCTGTAGTTCTGCCTGTGAGCAGCTCTCTCCACAAGAGTCCTGAGGCTGACTTTGTACCTGGCACTGGAGGCGAGGCCGGAGGTGGCCCACTCTTCCTTTTCTAGCCTGCCAGAGACCTTGAGAGCATTGAGGAAGCATTGAGGGGCTAGCGCCGTGGGGCGAGGGCTCATGGCACCTGTGCTCTGTGGACCCATGTGGGGAGCAAAGCGACAGGTTGGAGCTGCACTAACCCAGGCCCCAGGTCTGAGAGGCTGCTGACTCCCTGCCTGCATTTAGCCCCAGGAAGCTGAAACCTCAAACCATGTGGTGTTAGCGCCCAGGGCCTCGAAAGAGTCATTCAGAAACAGAGACCATGAATGGGCCATTCAGAAGGCTGGTGGCCCAGCCAGAACCAGAACCCAGCCACACCCCTGGGTCTGCACTCCAGACTGGGGTTCTTTCTGCCCTTCTCCAGCCTGTGTCTGCCTGGTGGTCACTCTGCGACATTTTCCTCTTTGGAGGCCCTTGCCTCTTCATGAGCCCCCCATCTCGCTGTAGCTTTGCCTTCTGACTTGGCTTTCCCCCACCCAGCAAGGGTTCTGAGCAGAAAGCCCTCCGTGTGAGAACCGCAGGGTTAGAAAGAGGCATGGGCACTAGAAATAGGGAGTGAATGCGGTCACCCTTGCTGGGACACCCTCAGCTGTCACCCCTGGGCTTTGTTGCTGAGGCTTTGTGCCGTCTTATTGTTTATCACCGGATGGAGCATCACGGGCTTCGCTCTGATGTCTCCAGTGGTGACAGTACCTGCCGCTCTGTTCTTCCAGAGTCTGTGGGGCACCCTGCTCCGCCAGGTGCTGCTGGTAACAGGCTCTGCATGTATCCGGGGCTCCAGCTCCCTCCCCACTGCCAGCCTCCCTCTGGACCATTCAATCTGTTCTCTTTTCCTTTTTCATTAAATGAGCAACCCTCCTCCCCCACAGCTGGAATGGTGGCATCGAATTTCAAGTGACCTTGACAAATCAGGGACCTGATCTTTTAAGAACAGGTTACAGTTAAGCGGGCAAGTTCAAGTCCACCCAGACAGGTTTCTGCAGAGGAGGGAGGAAACACCATGGGACGCCACCTGGGGATCACGTGGTGCCACCAACCATGCACCAGTGGATTCTGAGCCATGGTTGAGATGCAGGGAGTGGGATGGGGCTCAGGACCAGCTGCAAACCGACCCACCGTGAAAGTTTGTGGCACCTGCACCATCAGGGCGACATGCACTTTGGTTCTCTGTGTTTCAAAAAAGACCCAGAGGAATTGGAGCCACCCAAAGAAAGCAGAGTCAAACGCAAGGAAGAGAAAGCAGCAAGCCCTGCAGAGGTGTTGGGGGGTCAGTGCTCAGGCGTGGGAGTTCGAAGATCACCCTCAAGTACAGGAAGGAGTGGAGTAGTGTCCGTCTTCTCCTGGGACAGTCCTGAGAGATGGGCAGCATCCAGTTAGATCTGGTTCCATGGAACACCAGCTCTCCAGACGGTAGGAATAGGAATTACATGAAAAGGGCTTTGGGAGTCAGGCCAGTTTGGGAAATGCAGGGTTAAACCAAACTCACAAGTTTTCTTGAGGCAGGTTTTCCTGGAGCTCCTAGATAACTCCCAAGCATCACACTGTCCACGGACACGTGGGCCGCCTCCCAGGCTCTTGTGAGCCCAGCACCTGGTTTTTGCAGTCTTTTGTTTGGCTCTCCCACCCCCTTACACCCTTTGGGAACTGCTGAGTCAGATATACAGAAGAACAGTCACTGCGAGGGCTGTTAAACTCTCAGGAAAGGTACCAAAGTGCATGGCAGCGTTTGGCCCCAGTGAGCTGGAAAACACTTTCGTCTGGTCTTGAGATGTTTCCTGCAGCACAAGAGGTTGGCAGAGCAACCTCAGAACCTCTTCTGTCTCTGTTTATGCTTTTGTTCAGAAGCTTAGTACCAGGAATTAATCTCAGCTCCTTCCCAGAGGATTTTAGGCACACAGGGATCTTTTATTCTGCACTTCTCCAGTGATGCTTTCAACACAATTGTATCAAAACAGCCTAGGCTATTCACTTACAAGCCCTGCTTTTGCCCTGGGAATCTTAGCACCTCATTTTTTAGTAAGTACACTTGCAGATCCGGAGAGGGCAGGTGGAGGTATAATCCAGTGTCAGTCTGCAGTGGTGGGCCTGCCCTGGCCGTCTCCAAAGATGGGTGCTCTTCGGAACTGGCAGCCCCCTGCATGCTGTCTAATTGCCCCAAGAAAACAGTGACGTGTGTTTAGGAGCATGCTCCTGTTGGCCTCCATTTACAGGATCCTCTGTGTCAGAGGATCTCAGCCAGGCGTGATTTTGTTCACAAGGGACACTTGGCAATGCCTGGAGACATTTTGGTTGTCAAAACAGCAGGAAGGCAGACGTGCTCCTGTACCTATAGGTAGAGGCCAGGGCAGCTGCTCAGCACCCTAAGGTGCCCAGGACAGCTGCTCAGAGAATCTGTAGCCCAAAATGTCAACAGTGACCTGGCTGAGAAGCCCTGTCCCAGGTGGACCGCAGCATCCAGGGCATCCTGCGTGCTCGGCTTGCTCGTGGGTCCCTGCACACCCTGTGACTTCATTATCAGCTCAGAATGCACCTGGGGTTTGTTGTAGTGAGGGAAAGCTGAAATTGTTGCCAAAGGGGGAACTGTCTGCATCATCAAAGCTGCTTCTGTCATCTGTGTGAACATGCGCTTTTCTCTCTGCAG
Seq C2 exon
AACCTGAGAGCCAGAAGCAACAAAGATGCCAAGGATCCAACGACCAAGAACTCTCTGGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716:ENST00000305877:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.590
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(18.5=100)
A:
NA
C2:
PF0062115=RhoGEF=PD(8.7=38.1),PF0062115=RhoGEF=PU(28.6=95.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development