HsaINT0023692 @ hg19
Intron Retention
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6713418-6714093:-
Coord C1 exon
chr19:6714003-6714093
Coord A exon
chr19:6713521-6714002
Coord C2 exon
chr19:6713418-6713520
Length
482 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CCTCCTTGTCTGTCCCGTAGGTT
3' ss Score
11.96
Exon sequences
Seq C1 exon
TGCTGCCCAGTTTCGAGGTCATAGTGGAGCCTACAGAGAAATTCTACTACATCTATAACGAGAAGGGCCTGGAGGTCACCATCACCGCCAG
Seq A exon
GTGAGGGACTGGGGGTGGGGCCAGGTAAGAGCCAGGTGAGGGACCAGGTGAAGACCAGGTGGGGGACTGGGGGTGGAGTCAGGTGGGGGGCTGGAGATGGGACCAGGTGGGGGGCTGGGGGTGGAGTCAGGTGGGGGGCTGGGGGTGGGGAAGGTGGGGGGCTGGGGGTGGGGCAAGGTGAGGGGCTGGGGGTGGGACCAGGTGGGGGGCTGGGGGGTGGAGTCAGGTGGGGGCTGGGAGTGGGGAAGGTGGGGGGCTGGGGGTGGGGCCAGGTGAGGGGCTGGAGGTGGGACCATGTGGGGGGTGGGAGTGGGGCAAGGTGGGGGGCTGGGGGTGGGGCCAGGTGAGGGGCTGGAGGTGGGGCCAGGTGAGAGGCCAGCAGTGGGTTGGGGGCTCCAGTCTTCAGCACAGGCAGGAGAAGCTGGGGGAGATCCCATTCTCCAGGAGGGATGGACCTGAAGCCCTCCTTGTCTGTCCCGTAG
Seq C2 exon
GTTCCTCTACGGGAAGAAAGTGGAGGGAACTGCCTTTGTCATCTTCGGGATCCAGGATGGCGAACAGAGGATTTCCCTGCCTGAATCCCTCAAGCGCATTCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-C3:NM_000064:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCAGTTTCGAGGTCATAG
R:
GGAATGCGCTTGAGGGATTCA
Band lengths:
190-672
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)