HsaINT0025666 @ hg38
Intron Retention
Gene
ENSG00000198870 | STKLD1
Description
serine/threonine kinase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28669]
Coordinates
chr9:133394291-133395763:+
Coord C1 exon
chr9:133394291-133394409
Coord A exon
chr9:133394410-133395599
Coord C2 exon
chr9:133395600-133395763
Length
1190 bp
Sequences
Splice sites
5' ss Seq
GATGTGAGC
5' ss Score
4.72
3' ss Seq
GCTGTCCTCTCTCCGTGCAGGGC
3' ss Score
11.4
Exon sequences
Seq C1 exon
ACCCCTTTCGTAAGTCCTGGATGGCCCCTGAAGCCCTCAACTTCTCCTTCAGCCAGAAATCAGACATCTGGTCCCTGGGCTGCATCATTCTGGACATGACCAGCTGCTCCTTCATGGAT
Seq A exon
GTGAGCCGCCCTCCCTCCCCCACACCCCACATGCTGTTCCCCACGCGCCCAGGCCTGGGGAAAAGGCTTGGCCTCACCCTGCCTCCCCTCTGCATCCCTTCCCCTGGCTCTCTGCAGGCTGCACAGAGCCCTCTTCTCCACCTGCGAGGGGCCTGCCCTCCTCAGAACCCCTCAGCTTGCAGCACCTGCTGGGCTCTAGCAGGATAATGACAGCAGTGGTAATATTCAGACCATCCCACGCGACCCTCGCAGCAGCCCTCCAGGTGGTGTCACTGACTCTTGATGGAGAAAAGCCAAGTTCAGGTGCCCTTGTGAGCATGAAGGCTGCACGGAGTTGCAAGCAACGGGAACCCAGTGTGGGCCTGAACACACCTGGCTGTCTCATGCACAAGCCCCAGGCTGGTGTGGAGGTGCCTTCTCTCCTCCTGCACATCCTTAGCATGCAGCTCTTTCTCTCATCCCTGCTGGGGCCCCTGCACCATGGCCACAGCCTGTGGGCAGGAAGGAGGGGAGGCAGAGGGCCCCACTGGCCCCGCGAGCACTCCAAGGTCACTCTGGCTGCAGGGAGGCAGGGAAGTCCAGCCTGTCGCTTCCTATCCTCTATATGCAGAAGAGAAAAGTGGGGAAGGCCTGCCATGCCCAAAACAAGGAAGCTCCCCTTCTCCGCAGCACCACCTGCAGGCACCGAGGTCCCCAGAAAGGACAGACACCTGGCTGGACCCAGGTTCCCCATGGTCTCCCAGACCCCCAGACTCCACCTCTGAGAAGCACCTTGCCACTCCCTTCCTTTGAAAGACTCCCAGGGAAATGAGAGCCTTCCCACTTCGGAGGCTGTGTGACATCCTGGAAATTAGCCTGAGCTCCAGCCCCAGCCCAGGCAGTGTGACCCTGGGCATGCTCACACTCTGTGAAATGGGCATGCTGTCTTACTGGCTGGGTCTAGATCAGGGGGCTTTCTTGGCAGGACTCCACCCCGGGAGACAACCCGCTGGCTTCTCTGAAACTCCATTTCTTCTTATGGAAGAGCTTGGGGCCCCTGGGGTCTCTGGGCATTCTTGTAGACGGTGGCCACACCTGGCTCTCCCTGGTCTCCTCCTGGATTTCTTGGTCCCTGGTCGTCCCCTGCCCATGCTGGGACCTAGTTTTCATTTACTTAAGGGAATACACAGAGCTGTCCTCTCTCCGTGCAG
Seq C2 exon
GGCACAGAAGCCATGCATCTGCGGAAGTCCCTCCGCCAGAGCCCAGGCAGCCTGAAGGCCGTCCTGAAGACAATGGAGGAGAAGCAGATCCCGGATGTGGAAACCTTCAGGAATCTTCTGCCCTTGATGCTCCAGATCGACCCCTCGGATCGAATAACGATAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198870:ENST00000371957:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(14.4=100)
A:
NA
C2:
PF0006920=Pkinase=FE(20.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCCCTTTCGTAAGTCCTGGA
R:
TCGTTATTCGATCCGAGGGGT
Band lengths:
279-1469
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development