HsaINT0027355 @ hg38
Intron Retention
Gene
ENSG00000137225 | CAPN11
Description
calpain 11 [Source:HGNC Symbol;Acc:HGNC:1478]
Coordinates
chr6:44179952-44180499:+
Coord C1 exon
chr6:44179952-44180163
Coord A exon
chr6:44180164-44180459
Coord C2 exon
chr6:44180460-44180499
Length
296 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGG
5' ss Score
9.33
3' ss Seq
CTTTCAATCATTTTGCCCAGGGA
3' ss Score
6.19
Exon sequences
Seq C1 exon
TTTCAGAACATTCAGGATGTCCACTTGAAGAAGGAATTCTTCACGAAGTATCAGGACCACGGCTTCTCAGAGATCTTCACCAACTCACGGGAGGTGAGCAGCCAACTCCGGCTGCCTCCGGGGGAATATATCATTATTCCCTCCACCTTTGAGCCACACAGAGATGCTGACTTCCTGCTTCGGGTCTTCACCGAGAAGCACAGCGAGTCATG
Seq A exon
GTAAGGGGCTGCAGCTCACTGCTCCAAGGCCCGCCACCCAAGAGCTGCAGGATATCAAGCTCAGGGAGCTGCTGTCGGGTCCTCCCTCACTTTGTCCCTATTTTACAGTCAGGGAAACTGAGGCATGAGAAGGTGAAGTCCCAGTTAGTGGCAGAACCAGAACTAGAACTAGAACCCATATTCCATGGAGCTGCCCTATATTGCTTCAAAGACATGACATGACCCCCAGAGCACCCCACTAAAACCCCCACCTCCCTCCCCCTGGTAACTCTTGAGCTTTCAATCATTTTGCCCAG
Seq C2 exon
GGAATTGGATGAAGTCAACTATGCTGAGCAACTCCAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137225:ENST00000398776:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0106717=Calpain_III=FE(44.0=100)
A:
NA
C2:
PF0106717=Calpain_III=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATTCAGGATGTCCACTTGAAGA
R:
TCTTGGAGTTGCTCAGCATAGT
Band lengths:
244-540
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development